product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human ILDR2 (C-6His)
catalog :
C11F
quantity :
10 ug;50 ug;500 ug;1 mg
price :
75 USD
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
C11F
Product Name :
Recombinant Human ILDR2 (C-6His)
Product Type :
protein
Accession Number :
Q71H61
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
75 USD
sku :
C11F-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human Immunoglobulin-like Domain-containing Receptor 2 is produced by our Mammalian expression system and the target gene encoding Leu21-Glu186 is expressed with a 6His tag at the C-terminus.
Expression :
Human Cells
Background :
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic cells (DC2 cells, a subpopulation of polarized DCs that promotes Th2 differentiation). Recent publications reported that ILDR2 displayed negative regulatory functions on human and mouse T cells in various experimental systems. Fusion protein of ILDR2 lumenal domain with an Fc fragment, displays therapeutic effects in collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA). ILDR2 represents a novel B7-like ligand that exerts negative immune modulation via interaction with a putative counterpart receptor expressed on activated T cells.
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Packaging :
Ambient
ALTnames :
Angulin-3; C1orf32; Dbsm1; DJ782G3.1; ILDR2; immunoglobulin-like domain containing receptor 2; LISCH-Like
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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