product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human TRAIL R1 (C-6His）
catalog :
C08D
quantity :
10 ug;50 ug;500 ug;1 mg
price :
53 USD
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
C08D
Product Name :
Recombinant Human TRAIL R1 (C-6His）
Product Type :
protein
Accession Number :
O00220
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
53 USD
sku :
C08D-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 10A is produced by our Mammalian expression system and the target gene encoding Ala24-Asn239 is expressed with a 6His tag at the C-terminus.
Expression :
Human Cells
Background :
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF10 / TRAIL. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF1/TRAIL), and thus transduces cell death signal and induces cell apoptosis. TRAIL R1 can promote the activation of NF-kappa-B. TRAIL R1/CD261/TNFRSF1A induces apoptosis of many transformed cell lines but not of normal tissues, even though its death domain-containing receptor, DR4, is expressed on both cell types.
Endotoxin :
Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation :
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Packaging :
Ambient
ALTnames :
APO2; CD261 antigen; CD261; cytotoxic TRAIL receptor; DR4; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL-R1; TRAILR1
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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  • Fast turnaround time
  • Affordable cost


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