protein

Recombinant Human LAIR2 (C-Fc)

C02C

10 ug;50 ug;500 ug;1 mg

Recombinant Human LAIR2 (C-Fc)

protein

Q6ISS4

10 ug;50 ug;500 ug;1 mg

50

C02C-10ug

10ug;50ug;500ug;1mg

Recombinant Human Leukocyte-Associated Immunoglobulin-Like Receptor 2 is produced by our Mammalian expression system and the target gene encoding Gln22-Pro152 is expressed with a 6His tag at the C-terminus.

Human Cells

Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% amino acid identity across the signal sequence and extracellular domains; although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.

Less than 0.1 ng/ug (1 EU/ug)

Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2

Ambient

Leukocyte-Associated Immunoglobulin-Like Receptor 2; LAIR-2; CD306; LAIR2