product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human CD300LB (C-Fc)
catalog :
C00A
quantity :
10 ug;50 ug;500 ug;1 mg
more info or order :
product information
Catalog Number :
C00A
Product Name :
Recombinant Human CD300LB (C-Fc)
Product Type :
protein
Accession Number :
AAH28091.1
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
87
sku :
C00A-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human CD300LB is produced by our Mammalian expression system and the target gene encoding Ile55-His187 is expressed with a Fc tag at the C-terminus.
Expression :
Human Cells
Background :
CD300LB, also known as CD300b, LMIR5, CLM-7, and IREM‑3, is a glycoprotein member of the immunoglobulin superfamily. LMIR5 is expressed on the surface of myeloid lineage cells. It forms noncovalent cis‑homodimers and cis-heterodimers with other CD300 family proteins, and the composition of these dimers affects the cellular response. Antibody cross‑linking of LMIR5 induces mast cell granule release and cytokine production as well as its tyrosine phosphorylation of LMIR5 (in human). LMIR5 interacts with TIM1 and TIM4 which regulate T cell activation and are themselves binding partners. TIM1 interactions with LMIR5 mediate mast cell activation and the accumulation of neutrophils at sites of TIM1 up‑regulation on damaged renal tubule epithelial cells. Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Packaging :
Ambient
ALTnames :
CD300b; CLM-7; CLM-7; CMRF35-A2; IREM-3; IREM3; TREM-5; TREM5; CD300LB
more info or order :
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
Our reagents, your discovery!
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
- Guaranteed quality
- Flexible and care
- Fast turnaround time
- Affordable cost
Our reagents, your discovery!