product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human HE4/WFDC2 (C-His)
catalog :
BP271
quantity :
10 ug;50 ug;500 ug;1 mg
price :
110 USD
more info or order :
product information
Catalog Number :
BP271
Product Name :
Recombinant Human HE4/WFDC2 (C-His)
Product Type :
protein
Accession Number :
Q14508
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
110 USD
sku :
BP271-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human WAP Four-Disulfide Core Domain Protein 2 is produced by our Mammalian expression system and the target gene encoding Glu31-Phe124 is expressed with a 6His tag at the Cterminus.
Expression :
Human 293 Cells
Background :
WAP Four-Disulfide Core Domain Protein 2 (WFDC2) is a 25 kDa secreted glycoprotein containing two WAP domains. Mature human WFDC2 is 94 amino acids (aa) in length. It contains two WAP domains that likely mediate antiprotease and/or antimicrobial activity (aa 31 - 73 and 74 - 123). There are four potential splice variants. One shows a deletion of aa 27-74, while three others show aa substitutions: 28 aa for aa 75-124, 23 aa for aa 1 - 74, and 10 aa for aa 71-124. WFDC2 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed by a wide variety of epithelial cells, including respiratory epithelium, salivary gland mucous cells, breast duct epithelium, distal tubule renal epithelium, and epididymal epithelium. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2
Packaging :
Ambient
ALTnames :
WAP Four-Disulfide Core Domain Protein 2; Epididymal Secretory Protein E4; Major Epididymis-Specific Protein E4; Putative Protease Inhibitor WAP5; WFDC2; HE4; WAP5
more info or order :
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
Our reagents, your discovery!
Every customer is our VIP:
Flat rate charge for gene synthesis, recombinant protein production
- Guaranteed quality
- Flexible and care
- Fast turnaround time
- Affordable cost
Our reagents, your discovery!