product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Mesothelin (C-Fc)
catalog :
BP269
quantity :
10 ug;50 ug;500 ug;1 mg
price :
100 USD
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP269
Product Name :
Recombinant Human Mesothelin (C-Fc)
Product Type :
protein
Accession Number :
Q13421
Size :
10 ug;50 ug;500 ug;1 mg
List Price :
100 USD
sku :
BP269-10ug
Size option :
10ug;50ug;500ug;1mg
Product Description :
Recombinant Human Mesothelin is produced by our Mammalian expression system and the target gene encoding Glu296-Ser598 is expressed with a Fc tag at the C-terminus.
Expression :
Human 293 Cells
Background :
Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF- κ B and signal transducer and activator of transcription 3 (Stat3), inhibit apoptotic signaling and TNF- α - induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Lyophilized from a 0.2 um filtered solution of PBS,pH7.4
Packaging :
Ambient
ALTnames :
Megakaryocyte potentiating factor; mesothelin; Pre-pro-megakaryocyte-potentiating factor; soluble MPF mesothelin related protein; CAK1; MPF; MSLN; SMR; CAK1; CAK1 antigen
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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Flat rate charge for gene synthesis, recombinant protein production
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