product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Biotinylated Recombinant Human Fibronectin ED-B (N-His&Avi)
catalog :
BP137
quantity :
50 ug;500 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP137
Product Name :
Biotinylated Recombinant Human Fibronectin ED-B (N-His&Avi)
Product Type :
protein
Accession Number :
P02751
Size :
50 ug;500 ug
List Price :
250
sku :
BP137-50ug
Size option :
50ug;500ug
Product Description :
Recombinant Human Fibronectin is produced by our E.coli expression system and the target gene encoding Glu5-Thr95 is expressed with a 6His, Avi tag at the N-terminus.
Expression :
E. coli
Background :
Fibronectin is a high-molecular-weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. The occurrence of multiple isoforms results from alternative mRNA splicing of the ED-A, ED-B and III-CS regions, and subsequent post-translational modification. Fibronectin plays a critical role in cell adhesion, growth, migration, and differentiation, and it is important for the processes of wound healing and embryonic development. Altered fibronectin expression, degradation, and organization has been associated with a number of pathologies, including cancer and fibrosis. Studies of solid human tumors showed among the early signs of malignant transformation the fragmentation of pericellular fibronectin, concomitant with the increase of its production by the peritumoral stroma. These results have encouraged further investigations of the potential importance of fibronectin production and breakdown during cancer progression.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Supplied as a 0.2 um filtered solution of 50mM Tris, 150mM NaCl, pH7.2.
Packaging :
Dry ice/ice pack
ALTnames :
Fibronectin; FN1
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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