product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Interleukin-12 Subunit Beta/IL-12B (C-His)
catalog :
BP088
quantity :
50 ug;500 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP088
Product Name :
Recombinant Human Interleukin-12 Subunit Beta/IL-12B (C-His)
Product Type :
protein
Accession Number :
P29460
Size :
50 ug;500 ug
List Price :
315
sku :
BP088-50ug
Size option :
50ug;500ug
Product Description :
Recombinant Human Interleukin-12 Subunit Beta is produced by Human 293 Cells. The target gene encoding I23-S328 is expressed with a 6His tag at the C terminus.
Expression :
Human 293 Cells
Background :
Interleukin-12 (IL-12) is a heterodimeric pleiotropic cytokine that consists of IL12A (p35) and IL12B (p40) subunits. IL 12 is expressed by macrophages and B lymphocytes and act as a growth factor for activated T and NK cells, help enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Studies have shown that IL 12 is a key mediator of cellular-immunity and induces the differentiation of Th1 cells from precursor T helper cells. Based on its activities, it has been predicted that IL 12 may have therapeutic potential as a vaccine adjuvant that promotes cellular-immunity and as an anti-tumor and anti-viral agent. Interleukin-12 subunit beta (IL12B) has been shown to interact with IL23. A large excess of monomeric IL12B is also secreted by the cells producing IL12, and exhibits no demonstrable biological activity. Overexpression of IL12B gene has been shown to be associated with the pathogenesis of multiple sclerosis.
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Lyophilized frum a 0.2 um filtered solution of PBS, pH7.2
Packaging :
Ambient
ALTnames :
IL12B; CLMF; CLMF2; NKSF; NKSF2; p40
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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