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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Anterior gradient protein 2 homolog/AGR2(C-His)
catalog :
BP066
quantity :
50 ug;500 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP066
Product Name :
Recombinant Human Anterior gradient protein 2 homolog/AGR2(C-His)
Product Type :
protein
Accession Number :
O95994
Size :
50 ug;500 ug
List Price :
315
sku :
BP066-50ug
Size option :
50ug;500ug
Product Description :
Recombinant Human Anterior gradient protein 2 homolog is produced by Human 293 Cells. The target gene encoding R21-L175 is expressed with a 6His tag at the C terminus.
Expression :
Human 293 Cells
Background :
Anterior gradient 2 protein (AGR2) is a member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. The expression of AGR2 shows a positive correlation with the expression of estrogen receptor in breast carcinoma and a negative correlation with the expression of EGF receptor. Increased levels of extracellular AGR2 (eAGR2) have been correlated with poor prognosis in cancer patients, making it a potential biomarker. Studies revealed that increased AGR2 was associated with endoplasmic reticular homeostasis, possibly allowing tumor cells to overcome hypoxic stress and meet the increased protein demand of tumorigenesis, thereby preventing unfolded protein response-mediated apoptosis
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Supplied as a 0.2 um filtered solution of PBS, pH 7.4
Packaging :
Dry ice/ice pack
ALTnames :
Anterior Gradient Protein 2 Homolog; AG-2; hAG-2; HPC8; Secreted Cement Gland Protein XAG-2Homolog; AGR2; AG2
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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