product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human IL-3R alpha/CD123 (C-His)
catalog :
BP064
quantity :
50 ug;500 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP064
Product Name :
Recombinant Human IL-3R alpha/CD123 (C-His)
Product Type :
protein
Accession Number :
P26951
Size :
50 ug;500 ug
List Price :
250
sku :
BP064-50ug
Size option :
50ug;500ug
Product Description :
Recombinant Human IL-3R alpha is produced by Human 293 Cells. The target gene encoding K20-R305 is expressed with a 10His tag at the C terminus.
Expression :
Human 293 Cells
Background :
Interleukin 3 receptor alpha (IL3RA), also known as CD123, is a type I membrane protein that belongs to the type I cytokine receptor family. CD123 is strongly expressed in various leukemic blasts and leukemic stem cells and is showed to be an excellent target for the therapy of leukemias. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage‑committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL‑3 with low affinity. The beta subunit does not bind IL‑3 by itself but is required for the high‑affinity binding of IL‑3 to the heterodimeric receptor complex. Recent studies have demonstrated that CD123 is highly expressed on leukemia stem cells of patients with acute myeloid leukemia, and is correlated with tumor load and poor prognosis
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Lyophilized frum a 0.2 um filtered solution of PBS, pH 7.4
Packaging :
Ambient
ALTnames :
IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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