product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Cellular Tumor Antigen p53 (N-His)
catalog :
BP055
quantity :
50 ug;500 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP055
Product Name :
Recombinant Human Cellular Tumor Antigen p53 (N-His)
Product Type :
protein
Accession Number :
P04637
Size :
50 ug;500 ug
List Price :
315
sku :
BP055-50ug
Size option :
50ug;500ug
Product Description :
Recombinant human cellular tumor antigen p53 is produced by E.coli. The target gene encoding M1-D393 is expressed with a 6His tag at the N terminus.
Expression :
E. coli
Background :
p53 is a DNA-binding protein that belongs to the p53 family. p53 is expressed ubiquitously and its isoforms are expressed widely in normal tissues but in a tissue-dependent manner. It is well known for its key role as a tumor suppressor protein. p53 induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is also involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. Whilst the activation of p53 often leads to apoptosis, p53 inactivation facilitates tumor progression. Mutants of p53, which frequently occur in different human cancers, fail to bind the consensus DNA binding site, and thus cause the loss of tumor suppressor activity. Defects in TP53 are a cause of esophageal cancer, Li-Fraumeni syndrome, lung cancer and adrenocortical carcinoma.
Endotoxin :
Less than 0.1 ng/ug (1 EU/ug)
Formulation :
Supplied as a 0.2 um filtered solution of 2umM Tris,30umM NaCl ,5% glycerol ,umM DTT, 0.0umM ZnCl2, pH8.0
Packaging :
Dry ice/ice pack
ALTnames :
Antigen NY-CO-13; BCC7; FLJ92943; LFS1; LFS1TRP53; p53 tumor suppressor; p53; P53cellular tumor antigen p53; Phosphoprotein p53; TP53; transformation-related protein 53; TRP53; tumor protein p53; Tumor suppressor p53
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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