product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant SARS-CoV-2 Spike Protein (RBD) (C-His, HEK293)
catalog :
BP036
quantity :
100 ug;1 mg
product information
Catalog Number :
BP036
Product Name :
Recombinant SARS-CoV-2 Spike Protein (RBD) (C-His, HEK293)
Product Type :
protein
Accession Number :
P0DTC2
Size :
100 ug;1 mg
List Price :
350
sku :
BP036-100ug
Size option :
100ug;1mg
Product Description :
Recombinant SARS-CoV-2 Spike Protein is produced by HEK293. The target gene encoding 319-532 is expressed with a 8His tag at the C terminus.
Expression :
HEK293
Background :
SARS-CoV-2 Spike Protein is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM, etc. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Lyophilized frum a 0.2 um filtered solution of PBS, pH7.4
Packaging :
Ambient
ALTnames :
Spike Receptor Binding Domain; Spike RBD
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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