product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Human Collagen a-1(VIII) Chain/COL8A1 (C-6His)
catalog :
BP030
quantity :
50 ug;500 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP030
Product Name :
Recombinant Human Collagen a-1(VIII) Chain/COL8A1 (C-6His)
Product Type :
protein
Accession Number :
P27658
Size :
50 ug;500 ug
List Price :
440
sku :
BP030-50ug
Size option :
50ug;500ug
Product Description :
Recombinant Human Collagen alpha-1(VIII) Chain is produced by our Mammalian expression system and the target gene encoding Gly28-Met744 is expressed with a 6His tag at the C-terminus.
Expression :
Human Cells
Background :
Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. COL8A1 forms homotrimers or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrahedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 is mainly expressed in the subendothelium of large blood vessels. The expression level can be up-regulated during vascular injury, in atherosclerosis and in diabetes. COL8A1 is necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl, PH7.2
Packaging :
Dry ice/ice pack
ALTnames :
Collagen Alpha-1(VIII) Chain; Endothelial Collagen; Vastatin; COL8A1; C3orf7
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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