product summary
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company name :
Bon Opus Biosciences
product type :
protein
product name :
Recombinant Mouse VSIG4 (C-His)
catalog :
BP020
quantity :
50 ug;500 ug
more info or order :
Bon Opus Biosciences product webpage
product information
Catalog Number :
BP020
Product Name :
Recombinant Mouse VSIG4 (C-His)
Product Type :
protein
Accession Number :
F6TUL9
Size :
50 ug;500 ug
List Price :
250
sku :
BP020-50ug
Size option :
50ug;500ug
Product Description :
Recombinant Mouse V-Set and Ig Domain-Containing Protein 4 is produced by our Mammalian expression system and the target gene encoding His20-Pro187 is expressed with a 6His tag at the C-terminus.
Expression :
Human 293 Cells
Background :
V-set and immunoglobulin domain containing 4, also known as VSIG4, is a type I transmembrane glycoprotein that belongs to Ig superfamily and is a B7 family-related protein. The IgV domain of mouse VSIG4 shares 86% and 80% aa sequence identity with the IgV domains of rat and human VSIG4, respectively. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces, while no VSIG4 appears to be present in T and B cells. VSIG4 plays a role as a negative regulator of mouse/human T cell activation, and may be involved in the maintenance of peripheral T cell tolerance and/or unresponsiveness. VSIG4 also functions as a macrophage complement receptor by binding complement fragments C3b and iC3b. VSIG4 may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation.
Endotoxin :
Less than 0.1 EU/ug
Formulation :
Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4
Packaging :
Ambient
ALTnames :
Vsig4;V-set and immunoglobulin domain containing 4
more info or order :
Bon Opus Biosciences product webpage
company information
Bon Opus Biosciences
150 Essex St. Suite 301
Millburn, NJ 07041
sales@bonopusbio.com
http://www.bonopusbio.com
1-800-943-6396
headquarters: USA
Bon Opus Biosciences is a biotech company providing essential reagents to life science community. Bon Opus is derived from the Latin "Bonum Opus," which translates to good work. We are a team of like-minded and determined individuals, all sharing a vision for success. The catalog product includes primary antibody and recombinant proteins. The scope of services offered ranges from gene synthesis to recombinant protein expression, peptide synthesis, recombinant antibody production.

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