This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Bioss
product type :
antibody
product name :
PI3K p85 (5C11) Monoclonal Antibody
catalog :
bsm-33219M
quantity :
100 ul
price :
289.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5C11
reactivity :
mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
product information
sku :
bsm-33219M
name :
PI3K p85 (5C11) Monoclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Mouse
target protein :
PI3K p85
modification :
Unmodified
clonality :
Monoclonal
clone number :
5C11
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
1-110/724
source :
Recombinant mouse PI3K p85 Protein
gene id link :
Entrez Gene: 18708
swiss prot :
P26450
swiss prot link :
Swiss Prot: P26450
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (By similarity). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348926).
purification :
Purified by Protein G.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
Phosphatidylinositol 3-kinase regulatory subunit alpha; Pik3r1; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha
lead time :
3 to 5 business days.
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
http://biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.