GAPDH(3E12) Monoclonal Antibody | Bioss bsm-0978M product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Bioss

product type :

antibody

product name :

GAPDH(3E12) Monoclonal Antibody

catalog :

bsm-0978M

quantity :

100 ul

price :

269 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E12

reactivity :

human, mouse, rat

application :

western blot

citations: 7

Published Application/Species/Dilution	Reference
western blot; rat; 1:1000; fig 5	Pei H, Jiang T, Liu G, Li Z, Luo K, An J, et al. The Effect of Minimally Invasive Hematoma Aspiration on the JNK Signal Transduction Pathway after Experimental Intracerebral Hemorrhage in Rats. Int J Mol Sci. 2016;17: pubmed publisher
	Cui Y, Gu X. Proteomic changes of the porcine small intestine in response to chronic heat stress. J Mol Endocrinol. 2015;55:277-93 pubmed publisher
	Zhao T, Li Y, Wei W, Savage S, Zhou L, Ma D. Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. Neurobiol Dis. 2014;68:145-55 pubmed publisher
	Wei T, Liu Q, He F, Zhu W, Hu L, Guo L, et al. The role of N-acetylglucosaminyltransferases V in the malignancy of human hepatocellular carcinoma. Exp Mol Pathol. 2012;93:8-17 pubmed publisher
	Kang H, Liu M, Fan Y, Deng X. A potential gravity-sensing role of vascular smooth muscle cell glycocalyx in altered gravitational stimulation. Astrobiology. 2013;13:626-36 pubmed publisher
	Zhao H, Di J, Liu W, Liu H, Lai H, Lu Y. Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation. Behav Brain Res. 2013;241:228-34 pubmed publisher
	Zhang X, Zhang P, Yang Y, Qiu J, Kan Q, Liang H, et al. Regulation of pulmonary surfactant synthesis in fetal rat type II alveolar epithelial cells by microRNA-26a. Pediatr Pulmonol. 2014;49:863-72 pubmed publisher

product information

Catalog Number :

bsm-0978M

Product Name :

GAPDH(3E12) Monoclonal Antibody

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

100 ul

List Price :

269 USD

Clone :

3E12

Isotype :

IgG

CrossReactivity :

Human, Mouse, Rat, Sheep, Rabbit

Background :

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

ALTnames :

G3PD; GAPD; HEL-S-162eP; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH; CDABP47; OK/SW-cl.12

Epitope :

full length GAPDH protein

Purity :

Purified by Protein G.

Concentration :

1ug/ul

Storage :

Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

Uses :

Application Summary :

WB(1:100-1000)