This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Bioss
product type :
antibody
product name :
TNF-alpha (1F6) Monoclonal Antibody
catalog :
bsm-0387M
quantity :
100 ul
price :
279.5 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1F6
reactivity :
human
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
citations: 1
Reference
Zhang J, Zha W, Ye L, Wang F, Wang H, Shen T, et al. Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice. J Appl Toxicol. 2016;36:271-84 pubmed publisher
product information
Catalog Number :
bsm-0387M
Product Name :
TNF-alpha (1F6) Monoclonal Antibody
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
Unconjugated
Product Type :
Primary Antibody
Size :
100 ul
List Price :
279.5 USD
Clone :
1F6
Isotype :
IgG
CrossReactivity :
Human
Background :
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
ALTnames :
DIF; TNFA; TNFSF2; TNF-alpha; Tumor necrosis factor; Cachectin; Tumor necrosis factor ligand superfamily member 2; TNF-a; TNF
Epitope :
This antibody is produced using full length recombinant human TNF-alpha.
Localization :
Secreted, Membrane bound
Specificity :
This antibody is produced using full length recombinant TNF-alpha protein.
Purity :
Purified by Protein G.
Concentration :
1ug/ul
Storage :
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Uses :
WB, IHC-P, IF(IHC-P)
Application Summary :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.