NFKBIA(Tyr305) Polyclonal Antibody | Bioss bs-5515R product information

product summary

company name :

Bioss

product type :

antibody

product name :

NFKBIA(Tyr305) Polyclonal Antibody

catalog :

bs-5515R

quantity :

100 ul

price :

309.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Liu X, Zhang J, Han W, Wang Y, Liu Y, Zhang Y, et al. Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats.. Mol Med Rep. 2017;16:192-200 pubmed publisher
western blot; human; 1:500; loading ...; fig 3c	Tian Y, Wu X, Guo S, Ma L, Huang W, Zhao X. Minocycline attenuates sevoflurane-induced cell injury via activation of Nrf2. Int J Mol Med. 2017;39:869-878 pubmed publisher
western blot; rat	Zhao H, Zheng Q, Hu X, Shen H, Li F. Betulin attenuates kidney injury in septic rats through inhibiting TLR4/NF-κB signaling pathway. Life Sci. 2016;144:185-93 pubmed publisher
western blot; mouse	Gao W, Guo Y, Wang C, Lin Y, Yu L, Sheng T, et al. Indirubin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice through the inhibition of inflammation and the induction of Foxp3-expressing regulatory T cells. Acta Histochem. 2016;118:606-14 pubmed publisher
western blot; rat; 1:500; fig 5	Yu H, Shi L, Qi G, Zhao S, Gao Y, Li Y. Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Front Pharmacol. 2016;7:148 pubmed publisher
western blot; rat	Li Y, Zhang Q, Qi D, Zhang L, Yi L, Li Q, et al. Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-кB. J Headache Pain. 2016;17:49 pubmed publisher
western blot; rat	Yan X, Wu L, Li B, Meng X, Dai H, Zheng Y, et al. Cyanidin-3-O-glucoside Induces Apoptosis and Inhibits Migration of Tumor Necrosis Factor-α-Treated Rat Aortic Smooth Muscle Cells. Cardiovasc Toxicol. 2016;16:251-9 pubmed publisher

product information

sku :

bs-5515R

name :

NFKBIA(Tyr305) Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

NFKBIA Tyr305

modification :

Phosphorylation

modification site :

Tyr305

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

295-310/317

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Tyr305

gene id link :

Entrez Gene: 4792

swiss prot :

P25963

swiss prot link :

Swiss Prot: P25963

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

309.5 USD

background :

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

IKBA; MAD-3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3; NFKBIA; MAD3

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage