product summary
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company name :
Bioss
product type :
antibody
product name :
Bcl-2 Polyclonal Antibody
catalog :
bs-4563R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow, pig, sheep, rabbit
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section, other
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; sheep
  • immunocytochemistry; sheep; loading ...; fig 7
  • western blot; sheep; loading ...; fig 6e
Wang Y, Zhao Y, Yu S, Feng Y, Zhang H, Kou X, et al. Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis. Toxicol Appl Pharmacol. 2016;313:149-158 pubmed publisher
  • western blot; pig
  • western blot; cow; loading ...; fig 1c
Zhao Y, Zhang W, Liu X, Zhang P, Hao Y, Li L, et al. Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways. Sci Rep. 2016;6:37884 pubmed publisher
  • western blot; rabbit
Huang G, Zou J, Shi J, Zhang D, Peng H, Zhang Q, et al. Electroacupuncture stimulates remodeling of extracellular matrix by inhibiting apoptosis in a rabbit model of disc degeneration. Evid Based Complement Alternat Med. 2015;2015:386012 pubmed publisher
  • other; human
Chen L, Luo Y, Liu T, Yuan Y, Gu H, Yang Y, et al. Label-free electrochemical immunoassay of Bcl-2 protein expression on tumor cells. Talanta. 2015;132:479-85 pubmed publisher
  • western blot; pig
Wang C, Ma W, Su Y. NF-κB pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. Biol Trace Elem Res. 2013;153:403-10 pubmed publisher
  • immunohistochemistry - paraffin section; rabbit
Chen Y, Yan J, Wang X, Yu S, Wang Z, Zhang X, et al. In vivo and in vitro evaluation of effects of Mg-6Zn alloy on apoptosis of common bile duct epithelial cell. Biometals. 2014;27:1217-30 pubmed publisher
product information
sku :
bs-4563R
name :
Bcl-2 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Bcl-2
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
169-211/239
subcellular locations :
Cell membrane
source :
KLH conjugated synthetic peptide derived from human Bcl-2
gene id link :
Entrez Gene: 596
swiss prot :
P10415
swiss prot link :
Swiss Prot: P10415
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat, Pig, Rabbit
size :
100 ul
price :
289.5 USD
background :
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
Bcl-2; PPP1R5; Apoptosis regulator Bcl-2; BCL2
lead time :
3 to 5 business days.
more info or order :
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.