product summary
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company name :
Bioss
product type :
antibody
product name :
Talin Polyclonal Antibody
catalog :
bs-3619R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Bioss product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; rat
Dingyu W, Fanjie M, Zhengzheng D, Baosheng H, Chao Y, Yi P, et al. Regulation of Intracellular Structural Tension by Talin in the Axon Growth and Regeneration. Mol Neurobiol. 2016;53:4582-95 pubmed publisher
He J, Meng G, Yao R, Jiang B, Wu Y, Wu F. The essential role of inorganic substrate in the migration and osteoblastic differentiation of mesenchymal stem cells. J Mech Behav Biomed Mater. 2016;59:353-65 pubmed publisher
product information
sku :
bs-3619R
name :
Talin Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Talin1 + 2
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
1610-1660/2541
subcellular locations :
Cytoplasm, Cell membrane
source :
KLH conjugated synthetic peptide derived from human Talin 1.
gene id link :
Entrez Gene: 7094, 83660
swiss prot :
Q9Y4G6, Q9Y490
swiss prot link :
Swiss Prot: Q9Y4G6, Q9Y490
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
Talin, a multifunctional constituent of cell-substratum attachment sites, is a high molecular weight protein (225-270 kDa) found in variety of tissues and cell types. It is localized at a subset of adherens junctions, specialized cell-cell and cell-matrix associations that are characterized by the presence of filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with at least two other proteins that are localized at adhesion plaques, vinculin and integrin. Talin and vinculin have been shown to interact with each other and both have been proposed to be involved in generating the transmembrane connection, between the extracellular matrix and the cytoskeleton, that occurs at adhesion plaques. At physiological ionic strength, talin is an elongate, flexible, monomeric protein with the ability to self-associate into dimers at higher protein concentrations.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
TLN 1; ILWEQ; Talin 1; Talin; TLN; TLN1; TLN 2; Talin 2; Talin 2; TLN2.
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.