SQSTM1 Polyclonal Antibody | Bioss bs-2951R product information

product summary

company name :

Bioss

product type :

antibody

product name :

SQSTM1 Polyclonal Antibody

catalog :

bs-2951R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, cow

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; cow	Xia X, Gao Y, Zhang J, Wang L, Zhao S, Che Y, et al. Autophagy mediated by arginine depletion activation of the nutrient sensor GCN2 contributes to interferon-γ-induced malignant transformation of primary bovine mammary epithelial cells. Cell Death Discov. 2016;2:15065 pubmed publisher
western blot; human	Kuo H, Weng S, Chang A, Huang H, Lin H, Chuang J, et al. Altered mitochondrial dynamics and response to insulin in cybrid cells harboring a diabetes-susceptible mitochondrial DNA haplogroup. Free Radic Biol Med. 2016;96:116-29 pubmed publisher
western blot; human; loading ...; fig 2a	Cui X, Luo Y, Li C, Li Y, Wang Z. Changes of intracellular Ca2+ in quercetin-induced autophagy progression. Acta Biochim Biophys Sin (Shanghai). 2015;47:908-14 pubmed publisher
western blot; mouse	Chen Y, Wei G, Nie H, Lin Y, Tian H, Liu Y, et al. β-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice. Brain Res. 2014;1552:41-54 pubmed publisher

product information

sku :

bs-2951R

name :

SQSTM1 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

SQSTM1

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

80-130/440

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic peptide derived from human SQSTM1/Ubiquitin-binding protein p62

gene id link :

Entrez Gene: 8878

swiss prot :

Q13501

swiss prot link :

Swiss Prot: Q13501

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

p60; p62; A170; OSIL; PDB3; ZIP3; p62B; Sequestosome-1; EBI3-associated protein of 60 kDa; EBIAP; Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa; Ubiquitin-binding protein p62; SQSTM1; ORCA

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage