MAP1A/MAP1B LC3 A/B Antibody | Bioss bs-2912R product information

product summary

company name :

Bioss

product type :

antibody

product name :

MAP1A/MAP1B LC3 A/B Antibody

catalog :

bs-2912R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rat immunocytochemistry; rat	Lin C, Kuo Y, Chen T, Chien C. Quercetin-Rich Guava (Psidium guajava) Juice in Combination with Trehalose Reduces Autophagy, Apoptosis and Pyroptosis Formation in the Kidney and Pancreas of Type II Diabetic Rats. Molecules. 2016;21:334 pubmed publisher

product information

sku :

bs-2912R

name :

MAP1A/MAP1B LC3 A/B Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

MAP1A/MAP1B LC3 A/B

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

20-70/121

subcellular locations :

Cytoplasm, Cell membrane

source :

KLH conjugated synthetic peptide derived from human MAP1A/MAP1B LC3 B

gene id link :

Entrez Gene: 81631, 84557

applications :

IHC-P, IF(IHC-P)

applications with dilutions :

IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

MAP LC3 beta; LC3; Autophagy related protein LC3 A; Autophagy related protein LC3 B; Autophagy related ubiquitin like modier LC3 A; Autophagy related ubiquitin like modier LC3 B; MAP1 light chain 3 like protein 1; MAP1 light chain 3 like protein 2; MAP1A/1B light chain 3 A; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 A; MAP1A/MAP1B LC3 B; MAP1ALC3; MAP1BLC3; MAP1LC3A; MAP1LC3B; Microtubule associated protein 1 light chain 3 alpha; Microtubule associated protein 1 light chain 3 beta; Microtubule associated proteins 1A/1B light chain 3; Microtubule associated proteins 1A/1B light chain 3A; Microtubule associated proteins 1A/1B light chain 3B.microtubule-associated proteins 1A/1B light chain 3 beta 2

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage