product summary
company name :
Bioss
product type :
antibody
product name :
Lymphocyte Activation Gene 3 Antibody
catalog :
bs-2646R
quantity :
100 ul
price :
279 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Bioss product webpage
citations: 2
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 1a
Chen Y, Huang Y, Lu X, Wang G, Chi P. Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation. Oncol Rep. 2018;40:3370-3380 pubmed publisher
Parodi A, Battaglia F, Kalli F, Ferrera F, Conteduca G, Tardito S, et al. CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes. Cancer Immunol Immunother. 2013;62:851-62 pubmed publisher
product information
sku :
bs-2646R
name :
Lymphocyte Activation Gene 3 Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Lymphocyte Activation Gene 3
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
210-260/525
subcellular locations :
Extracellular
source :
KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
gene id link :
Entrez Gene: 297596
swiss prot :
Q5BK54
swiss prot link :
Swiss Prot: Q5BK54
applications :
WB, IHC-P, IF(IHC-P), IF(ICC)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
279 USD
background :
Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
CD223; Lymphocyte activation gene 3 protein; LAG-3; Lag3
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
http://biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.