ERK1 + 2 Polyclonal Antibody | Bioss bs-2637R product information

product summary

company name :

Bioss

product type :

antibody

product name :

ERK1 + 2 Polyclonal Antibody

catalog :

bs-2637R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, rabbit

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 10

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Zhao H, Xue Y, Guo Y, Sun Y, Liu D, Wang X. Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension. Int Immunopharmacol. 2017;42:115-121 pubmed publisher
western blot; rat	Liu X, Zhang J, Han W, Wang Y, Liu Y, Zhang Y, et al. Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats. Mol Med Rep. 2017;16:192-200 pubmed publisher
western blot; rat	Cong L, Chen W. Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats. Basic Clin Pharmacol Toxicol. 2016;119:193-201 pubmed publisher
western blot; rat	Zhao H, Liu Z, Liu W, Han X, Zhao M. Betulin attenuates lung and liver injuries in sepsis. Int Immunopharmacol. 2016;30:50-6 pubmed publisher
western blot; rat; 1:500; fig 5	Yu H, Shi L, Qi G, Zhao S, Gao Y, Li Y. Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Front Pharmacol. 2016;7:148 pubmed publisher
western blot; mouse	Chen W, Bao Y, Chen X, Burton J, Gong X, Gu D, et al. Mycobacterium tuberculosis PE25/PPE41 protein complex induces activation and maturation of dendritic cells and drives Th2-biased immune responses. Med Microbiol Immunol. 2016;205:119-31 pubmed publisher
immunohistochemistry - paraffin section; rat	Wang T, Zhai L, Guo Y, Pei H, Zhang M. Picroside II has a neuroprotective effect by inhibiting ERK1/2 activation after cerebral ischemic injury in rats. Clin Exp Pharmacol Physiol. 2015;: pubmed publisher
immunohistochemistry - paraffin section; rat	Wang T, Zhao L, Guo Y, Zhang M, Pei H. Picroside II Inhibits Neuronal Apoptosis and Improves the Morphology and Structure of Brain Tissue following Cerebral Ischemic Injury in Rats. PLoS ONE. 2015;10:e0124099 pubmed publisher
western blot; rabbit	An P, Dang H, Shi X, Ye B, Wu X. "Qufeng Tongluo" acupuncture prevents the progression of glomerulonephritis by decreasing renal sympathetic nerve activity. J Ethnopharmacol. 2014;155:277-84 pubmed publisher
western blot; human	Xu S, Guo P, Shi Q, He D, Gao Y, Zhang H. Acyldepsipeptides inhibit the growth of renal cancer cells through G1 phase cell cycle arrest. Biochem Biophys Res Commun. 2013;438:468-72 pubmed publisher

product information

sku :

bs-2637R

name :

ERK1 + 2 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

ERK1 + 2

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

320-356/358

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic peptide derived from mouse ERK2

gene id link :

Entrez Gene: 26413

swiss prot :

P63085

swiss prot link :

Swiss Prot: P63085

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Rabbit

size :

100 ul

price :

289.5 USD

background :

The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

ERK; Erk2; MAPK2; PRKM2; Prkm1; C78273; p41mapk; p42mapk; AA47128; AU18647; 93612K14Rik; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; Mapk1; Mapk

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage