product summary
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company name :
Bioss
product type :
antibody
product name :
Integrin alpha 2b Polyclonal Antibody
catalog :
bs-2636R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Bioss product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; fig 6
Sugiyama M, Gamage A, Zyla R, Armstrong S, Advani S, Advani A, et al. Influenza Virus Infection Induces Platelet-Endothelial Adhesion Which Contributes to Lung Injury. J Virol. 2016;90:1812-23 pubmed publisher
Lê V, Schneider J, Boergeling Y, Berri F, Ducatez M, Guerin J, et al. Platelet activation and aggregation promote lung inflammation and influenza virus pathogenesis. Am J Respir Crit Care Med. 2015;191:804-19 pubmed publisher
Araki T, Ogawara K, Suzuki H, Kawai R, Watanabe T, Ono T, et al. Augmented EPR effect by photo-triggered tumor vascular treatment improved therapeutic efficacy of liposomal paclitaxel in mice bearing tumors with low permeable vasculature. J Control Release. 2015;200:106-14 pubmed publisher
Mei Y, Yin N, Jin X, He J, Yin Z. The regulatory role of the adrenergic agonists phenylephrine and isoproterenol on fetal hemoglobin expression and erythroid differentiation. Endocrinology. 2013;154:4640-9 pubmed publisher
product information
sku :
bs-2636R
name :
Integrin alpha 2b Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Integrin alpha 2b/CD41
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
370-420/1033
subcellular locations :
Extracellular
source :
KLH conjugated synthetic peptide derived from mouse Integrin alpha 2b
gene id link :
Entrez Gene: 16399
swiss prot :
Q9QUM0
swiss prot link :
Swiss Prot: Q9QUM0
applications :
IHC-P, IF(IHC-P)
applications with dilutions :
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
CD41; CD41B; GpIIb; AI172977; alphaIIb; Integrin alpha-IIb; GPalpha IIb; Platelet membrane glycoprotein IIb; Itga2b
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.