product summary
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company name :
Bioss
product type :
antibody
product name :
NFKBIA(Ser32/36) Polyclonal Antibody
catalog :
bs-2513R
quantity :
100 ul
price :
309.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Bioss product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; rat
Fu J, Shi Q, Song X, Xia X, Su C, Liu Z, et al. Tetrachlorobenzoquinone exhibits neurotoxicity by inducing inflammatory responses through ROS-mediated IKK/IκB/NF-κB signaling. Environ Toxicol Pharmacol. 2016;41:241-50 pubmed publisher
product information
sku :
bs-2513R
name :
NFKBIA(Ser32/36) Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
NFKBIA Ser32/36
specificity :
These phosphorylation sites are homologous among the species listed.
modification :
Phosphorylation
modification site :
Ser32/36
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
20-50/317
subcellular locations :
Cytoplasm, Nucleus
source :
KLH conjugated synthetic phosphopeptide derived from human IKB alpha around the phosphorylation site of Ser32/36
gene id link :
Entrez Gene: 4792
swiss prot :
P25963
swiss prot link :
Swiss Prot: P25963
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
309.5 USD
background :
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
IKBA; MAD-3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3; NFKBIA; MAD3
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.