product summary
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company name :
Bioss
product type :
antibody
product name :
CD80 Polyclonal Antibody
catalog :
bs-2211R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human
Han S, Wang C, Qin X, Xia J, Wu A. LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4. J Exp Clin Cancer Res. 2017;36:83 pubmed publisher
  • western blot; mouse; 1:2000; fig 4
Chen Q, Li R, Zhao X, Liang B, Ma S, Li Z, et al. Prevention of ultraviolet radiation‑induced immunosuppression by sunscreen in Candida albicans‑induced delayed‑type hypersensitivity. Mol Med Rep. 2016;14:202-8 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Ju H, Xing W, Yang J, Zheng Y, Jia X, Zhang B, et al. An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model. BMC Immunol. 2016;17:31 pubmed
  • immunohistochemistry - paraffin section; mouse
Wang S, Hu Z, Wang X, Gu C, Gao Z, Cao W, et al. 5-Aminolevulinic acid-mediated sonodynamic therapy reverses macrophage and dendritic cell passivity in murine melanoma xenografts. Ultrasound Med Biol. 2014;40:2125-33 pubmed publisher
product information
sku :
bs-2211R
name :
CD80 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
CD80
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
270-321/321
subcellular locations :
Cytoplasm
source :
KLH conjugated synthetic peptide derived from rat CD80
gene id link :
Entrez Gene: 25408
swiss prot :
G3V671
swiss prot link :
Swiss Prot: G3V671
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
B7-1; Activation B7 1 antigen; Activation B71 antigen; B lymphocyte activation antigen B7; B7; BB1; CD 80; CD28 antigen ligand 1 B7 1 antigen; CD28 antigen ligand 1 B71 antigen; CD28LG; CD28LG1; CD80 antigen; CD80 antigen precursor;CD80 molecule; Costimulatory factor CD80; CTLA 4 counter receptor B7.1; CTLA-4 counter-receptor B7.1; LAB 7; LAB7; T lymphocyte activation antigen CD80; CD80_MOUSE.
lead time :
3 to 5 business days.
more info or order :
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.