p38 MAPK (Thr180 + Tyr182) Antibody | Bioss bs-2210R product information

product summary

company name :

Bioss

product type :

antibody

product name :

p38 MAPK (Thr180 + Tyr182) Antibody

catalog :

bs-2210R

quantity :

100 ul

price :

309.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

goat, human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human	Iriyama N, Hatta Y, Takei M. Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes. Cancer Med. 2016;5:3223-3234 pubmed publisher
western blot; goat	Li M, Yu M, Liu C, Zhu H, Hua J. Expression of miR-34c in response to overexpression of Boule and Stra8 in dairy goat male germ line stem cells (mGSCs). Cell Biochem Funct. 2013;31:281-8 pubmed publisher

product information

sku :

bs-2210R

name :

p38 MAPK (Thr180 + Tyr182) Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

p38 MAPK Thr180 + Tyr182

modification :

Phosphorylation

modification site :

Thr180 + Tyr182

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

160-200/360

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic phosphopeptide derived from human p38 MAPK around the phosphorylation site of(Thr180/Tyr182)

gene id link :

Entrez Gene: 1432

swiss prot :

Q16539

swiss prot link :

Swiss Prot: Q16539

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Goat

size :

100 ul

price :

309.5 USD

background :

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; MAP kinase MXI2; MAX-interacting protein 2; Mitogen-activated protein kinase p38 alpha; MAP kinase p38 alpha; Stress-activated protein kinase 2a; MAPK14

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage