GAPDH Polyclonal Antibody | Bioss bs-2188R product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Bioss

product type :

antibody

product name :

GAPDH Polyclonal Antibody

catalog :

bs-2188R

quantity :

100 ul

price :

269 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

citations: 6

Published Application/Species/Dilution	Reference
western blot; rat; 1:300; fig 2	Jia L, Song N, Yang G, Ma Y, Li X, Lu R, et al. Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. Mol Med Rep. 2016;13:4627-35 pubmed publisher
	Xiao L, Song Y, Huang W, Yang S, Fu J, Feng X, et al. Expression of SOX2, NANOG and OCT4 in a mouse model of lipopolysaccharide-induced acute uterine injury and intrauterine adhesions.. Reprod Biol Endocrinol. 2017;15:14 pubmed publisher
	Shao G, Qian D, Wang H, Yan Z, Hu M, Wang T, et al. Construction of the plasmid coding for the expression of the EGFP-M-IL-2((88)Arg, (125)Ala) fusion protein and the anti-tumor effects exerted by the fusion protein in HeLa-60 cells. Oncol Lett. 2015;9:2729-2735 pubmed
	Hou Y, Liu L, Chai J, Yu Y, Duan H, Hu Q, et al. Lipopolysaccharide pretreatment inhibits LPS-induced human umbilical cord mesenchymal stem cell apoptosis via upregulating the expression of cellular FLICE-inhibitory protein. Mol Med Rep. 2015;12:2521-8 pubmed publisher
	Zhang X, Shi H, Lin S, Ba M, Cui S. MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting beclin-1-mediated autophagy. Oncol Rep. 2015;34:1557-64 pubmed publisher
	Song Y, Xiao L, Fu J, Huang W, Wang Q, Zhang X, et al. Increased expression of the pluripotency markers sex-determining region Y-box 2 and Nanog homeobox in ovarian endometriosis. Reprod Biol Endocrinol. 2014;12:42 pubmed publisher

product information

Catalog Number :

bs-2188R

Product Name :

GAPDH Polyclonal Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Product Type :

Primary Antibody

Size :

100 ul

List Price :

269 USD

Isotype :

IgG

CrossReactivity :

Human, Mouse, Rat

Background :

Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

ALTnames :

G3PD; GAPD; HEL-S-162eP; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH; CDABP47; OK/SW-cl.12

Epitope :

GAPDH protein of rabbit

Localization :

Cytoplasm

Purity :

Purified by Protein A.

Concentration :

1ug/ul

Storage :

Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

Uses :

WB, IHC-P, IF(IHC-P)

Application Summary :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)