Ki-67 (Proliferation Marker) Antibody | Bioss bs-2130R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Ki-67 (Proliferation Marker) Antibody

catalog :

bs-2130R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse	Thompson C, Rahim S, Arnold J, Hielscher A. Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands.. PLoS ONE. 2017;12:e0172067 pubmed publisher
immunohistochemistry - paraffin section; mouse	Luo X, Chen M, Zhang Y, Chen Z, Li X. Pharmacokinetics and antitumor efficacy of micelles assembled from multiarmed amphiphilic copolymers with drug conjugates in comparison with drug-encapsulated micelles. Eur J Pharm Biopharm. 2016;98:9-19 pubmed publisher
immunohistochemistry - paraffin section; rat	Drel V, Tan C, Barnes J, Gorin Y, Lee D, Wagner B. Centrality of bone marrow in the severity of gadolinium-based contrast-induced systemic fibrosis. FASEB J. 2016;30:3026-38 pubmed publisher
immunohistochemistry - paraffin section; mouse	Li X, Zhu X, Qiu L. Constructing aptamer anchored nanovesicles for enhanced tumor penetration and cellular uptake of water soluble chemotherapeutics. Acta Biomater. 2016;35:269-79 pubmed publisher
immunohistochemistry - paraffin section; mouse	Yang F, Li J, Zhu J, Wang D, Chen S, Bai X. Hydroxysafflor yellow A inhibits angiogenesis of hepatocellular carcinoma via blocking ERK/MAPK and NF-κB signaling pathway in H22 tumor-bearing mice. Eur J Pharmacol. 2015;754:105-14 pubmed publisher
immunohistochemistry - paraffin section; mouse	Zhang J, Song S, Pang Q, Zhang R, Wan Y, Yuan D, et al. Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice. World J Gastroenterol. 2015;21:4195-209 pubmed publisher
immunohistochemistry - paraffin section; mouse	Ye Q, Zheng Y, Fan S, Qin Z, Li N, Tang A, et al. Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice. PLoS ONE. 2014;9:e103298 pubmed publisher
immunohistochemistry - paraffin section; mouse	Pan D, She W, Guo C, Luo K, Yi Q, Gu Z. PEGylated dendritic diaminocyclohexyl-platinum (II) conjugates as pH-responsive drug delivery vehicles with enhanced tumor accumulation and antitumor efficacy. Biomaterials. 2014;35:10080-92 pubmed publisher
immunohistochemistry - paraffin section; mouse	Li N, Li N, Yi Q, Luo K, Guo C, Pan D, et al. Amphiphilic peptide dendritic copolymer-doxorubicin nanoscale conjugate self-assembled to enzyme-responsive anti-cancer agent. Biomaterials. 2014;35:9529-45 pubmed publisher
immunohistochemistry - paraffin section; mouse	Zhao Y, Li Q, Katzenellenbogen B, Lau L, Taylor R, Bagchi I, et al. Estrogen-induced CCN1 is critical for establishment of endometriosis-like lesions in mice. Mol Endocrinol. 2014;28:1934-47 pubmed publisher
immunohistochemistry - paraffin section; human	Kim K, Lim H, Kim Y, Kim S, Kim Y, Tian C, et al. The oncoprotein, gankyrin, is up-regulated in middle ear cholesteatoma. Acta Otolaryngol. 2014;134:238-43 pubmed publisher
immunohistochemistry - paraffin section; human	Ma Y, Yu S, He X, Xu Y, Wu F, Xia Y, et al. Involvement of c-KIT mutation in the development of gastrointestinal stromal tumors through proliferation promotion and apoptosis inhibition. Onco Targets Ther. 2014;7:637-43 pubmed publisher
immunohistochemistry - paraffin section; mouse	Luo X, Zhang H, Chen M, Wei J, Zhang Y, Li X. Antimetastasis and antitumor efficacy promoted by sequential release of vascular disrupting and chemotherapeutic agents from electrospun fibers. Int J Pharm. 2014;475:438-49 pubmed publisher
western blot; mouse	Yuan Q, Han J, Cong W, Ge Y, Ma D, Dai Z, et al. Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity. Int J Nanomedicine. 2014;9:4829-46 pubmed publisher
	He N, Chen Z, Yuan J, Zhao L, Chen M, Wang T, et al. Tumor pH-Responsive Release of Drug-Conjugated Micelles from Fiber Fragments for Intratumoral Chemotherapy. ACS Appl Mater Interfaces. 2017;9:32534-32544 pubmed publisher
	Zhao Y, Chen Y, Kuang Y, Bagchi M, Taylor R, Katzenellenbogen J, et al. Multiple Beneficial Roles of Repressor of Estrogen Receptor Activity (REA) in Suppressing the Progression of Endometriosis. Endocrinology. 2016;157:900-12 pubmed publisher
	Antognelli C, Gambelunghe A, Muzi G, Talesa V. Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica Min-U-Sil 5: Transformation into a neoplastic-like phenotype. Free Radic Biol Med. 2016;92:110-25 pubmed publisher
	Olianas M, Dedoni S, Onali P. Antidepressants activate the lysophosphatidic acid receptor LPA(1) to induce insulin-like growth factor-I receptor transactivation, stimulation of ERK1/2 signaling and cell proliferation in CHO-K1 fibroblasts. Biochem Pharmacol. 2015;95:311-23 pubmed publisher

product information

sku :

bs-2130R

name :

Ki-67 (Proliferation Marker) Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Ki-67 proliferation Marker

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

1250-1300/3256

subcellular locations :

Nucleus

source :

KLH conjugated synthetic peptide derived from human Ki67

gene id link :

Entrez Gene: 4288

swiss prot :

P46013

swiss prot link :

Swiss Prot: P46013

applications :

IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Proliferation Marker Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

KIA; MIB-; MIB-1; PPP1R15; Antigen KI-67; MKI67

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage