TNF alpha Polyclonal Antibody | Bioss bs-2081R product information

product summary

company name :

Bioss

product type :

antibody

product name :

TNF alpha Polyclonal Antibody

catalog :

bs-2081R

quantity :

100 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, domestic rabbit

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Bioss product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:100; loading ...; fig 4	Lee S, Chen Y, Chien C, Yan Y, Chen H, Chuang H, et al. Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model. PLoS ONE. 2021;16:e0254587 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...; fig 4c	Huo S, Shi W, Ma H, Yan D, Luo P, Guo J, et al. Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene. Oxid Med Cell Longev. 2021;2021:6699054 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3a	Cao Y, Xu Y, Auchoybur M, Chen W, He S, Qin W, et al. Regulatory role of IKKɑ in myocardial ischemia/reperfusion injury by the determination of M1 versus M2 polarization of macrophages. J Mol Cell Cardiol. 2018;123:1-12 pubmed publisher
immunohistochemistry - paraffin section; mouse	Wang X, Tang Y, Shen R, Chen J, Chen G, Luo G, et al. Hepatocyte growth factor (HGF) optimizes oral traumatic ulcer healing of mice by reducing inflammation. Cytokine. 2017;99:275-280 pubmed publisher
western blot; human	Han S, Wang C, Qin X, Xia J, Wu A. LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4. J Exp Clin Cancer Res. 2017;36:83 pubmed publisher
immunohistochemistry - frozen section; mouse	Dong M, Zhou C, Ji L, Pan B, Zheng L. AG1296 enhances plaque stability via inhibiting inflammatory responses and decreasing MMP-2 and MMP-9 expression in ApoE-/- mice. Biochem Biophys Res Commun. 2017;489:426-431 pubmed publisher
immunohistochemistry - paraffin section; rat	Shi X, Yu W, Liu L, Liu W, Zhang X, Yang T, et al. Panax notoginseng saponins administration modulates pro- /anti-inflammatory factor expression and improves neurologic outcome following permanent MCAO in rats. Metab Brain Dis. 2017;32:221-233 pubmed publisher
immunohistochemistry; rat; 1:300; fig 8	Qian H, Guan X, Bian Z. FSH aggravates bone loss in ovariectomised rats with experimental periapical periodontitis. Mol Med Rep. 2016;14:2997-3006 pubmed publisher
immunohistochemistry - paraffin section; domestic rabbit	Ji M, Wang Y, Wang L, Chen L, Li J. Protective effect of Xuebijing injection against acute lung injury induced by left ventricular ischemia/reperfusion in rabbits. Exp Ther Med. 2016;12:51-58 pubmed
western blot; mouse	Du J, Niu X, Wang R, Zhao S, Kong L, Zhang Y, et al. TLR4â€‘dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice. Mol Med Rep. 2016;13:2159-66 pubmed publisher
	Lennikov A, Mirabelli P, Mukwaya A, Schaupper M, Thangavelu M, Lachota M, et al. Selective IKK2 inhibitor IMD0354 disrupts NF-ÎºB signaling to suppress corneal inflammation and angiogenesis. Angiogenesis. 2018;21:267-285 pubmed publisher
	Bertuglia A, Pagliara E, Grego E, Ricci A, Brkljača Bottegaro N. Pro-inflammatory cytokines and structural biomarkers are effective to categorize osteoarthritis phenotype and progression in Standardbred racehorses over five years of racing career. BMC Vet Res. 2016;12:246 pubmed
	Sun C, Zeng R, Cao G, Song Z, Zhang Y, Liu C. Vibration Training Triggers Brown Adipocyte Relative Protein Expression in Rat White Adipose Tissue. Biomed Res Int. 2015;2015:919401 pubmed publisher

product information

sku :

bs-2081R

name :

TNF alpha Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

TNF alpha

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

180-230/235

subcellular locations :

Extracellular

source :

KLH conjugated synthetic peptide derived from mouse TNF-alpha

gene id link :

Entrez Gene: 21926

swiss prot :

P06804

swiss prot link :

Swiss Prot: P06804

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

background :

Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

DIF; Tnfa; TNF-a; TNFSF2; Tnfsf1a; TNFalpha; TNF-alpha; Tumor necrosis factor; Cachectin; Tumor necrosis factor ligand superfamily member 2; Tnf

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage