STAT3 (Tyr705) Polyclonal Antibody | Bioss bs-1658R product information

product summary

company name :

Bioss

product type :

antibody

product name :

STAT3 (Tyr705) Polyclonal Antibody

catalog :

bs-1658R

quantity :

100 ul

price :

309.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken, pig

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; human	Gao L, Wang L, Sun Z, Li H, Wang Q, Yi C, et al. Morusin shows potent antitumor activity for human hepatocellular carcinoma in vitro and in vivo through apoptosis induction and angiogenesis inhibition. Drug Des Devel Ther. 2017;11:1789-1802 pubmed publisher
western blot; chicken	Zhang Y, Zhang L, Zuo Q, Wang Y, Zhang Y, Xu Q, et al. JAK-STAT signaling regulation of chicken embryonic stem cell differentiation into male germ cells. In Vitro Cell Dev Biol Anim. 2017;53:728-743 pubmed publisher
flow cytometry; human	Iriyama N, Hatta Y, Takei M. Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes. Cancer Med. 2016;5:3223-3234 pubmed publisher
immunohistochemistry - paraffin section; pig immunocytochemistry; pig	Sur S, Swier V, Radwan M, Agrawal D. Increased Expression of Phosphorylated Polo-Like Kinase 1 and Histone in Bypass Vein Graft and Coronary Arteries following Angioplasty. PLoS ONE. 2016;11:e0147937 pubmed publisher
western blot; mouse	Lee E, Lee S, Kim J, Kim K, Yang S, Jeong K, et al. Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells. PLoS ONE. 2016;11:e0146463 pubmed publisher
western blot; pig	Yang H, Sun C, Sun C, Qi R. Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte. Mol Biol Rep. 2012;39:9113-22 pubmed publisher

product information

sku :

bs-1658R

name :

STAT3 (Tyr705) Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

STAT3 Tyr705

modification :

Phosphorylation

modification site :

Tyr705

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

685-725/770

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Tyr705

gene id link :

Entrez Gene: 6774

swiss prot :

P40763

swiss prot link :

Swiss Prot: P40763

applications :

WB, FCM, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Pig

size :

100 ul

price :

309.5 USD

background :

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage