ERK1(T202/Y204)+ERK2(T183/Y185) Antibody | Bioss bs-1646R product information

product summary

company name :

Bioss

product type :

antibody

product name :

ERK1(T202/Y204)+ERK2(T183/Y185) Antibody

catalog :

bs-1646R

quantity :

100 ul

price :

309.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse	Hirata A, Katayama K, Tsuji T, Imura H, Natsume N, Sugahara T, et al. Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016;56:172-9 pubmed publisher
flow cytometry; human	Iriyama N, Hatta Y, Takei M. Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes. Cancer Med. 2016;5:3223-3234 pubmed publisher
western blot; rat	Wang J, Fu X, Jiang C, Yu L, Wang M, Han W, et al. Bone marrow mononuclear cell transplantation promotes therapeutic angiogenesis via upregulation of the VEGF-VEGFR2 signaling pathway in a rat model of vascular dementia. Behav Brain Res. 2014;265:171-80 pubmed publisher

product information

sku :

bs-1646R

name :

ERK1(T202/Y204)+ERK2(T183/Y185) Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

ERK1 Thr202/Tyr204+ERK2 Thr183/Tyr185

modification :

Phosphorylation

modification site :

Thr183/Tyr185

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

155-205/360

subcellular locations :

Cytoplasm

source :

KLH conjugated synthetic phosphopeptide derived from human ERK2 around the phosphorylation site of Thr183/Tyr185

gene id link :

Entrez Gene: 5594,5595

swiss prot :

P28482

swiss prot link :

Swiss Prot: P28482

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

309.5 USD

background :

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

ERK; p38; p4; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; Extracellular signal-regulated kinase 2; MAP kinase isoform p42; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; MAPK1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage