JNK1+2+3 (T183+Y185) Polyclonal Antibody | Bioss bs-1640R product information

product summary

company name :

Bioss

product type :

antibody

product name :

JNK1+2+3 (T183+Y185) Polyclonal Antibody

catalog :

bs-1640R

quantity :

100 ul

price :

309.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Zhao H, Xue Y, Guo Y, Sun Y, Liu D, Wang X. Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension. Int Immunopharmacol. 2017;42:115-121 pubmed publisher
western blot; rat	Ning C, Wang X, Gao S, Mu J, Wang Y, Liu S, et al. Chicory inulin ameliorates type 2 diabetes mellitus and suppresses JNK and MAPK pathways in vivo and in vitro. Mol Nutr Food Res. 2017;: pubmed publisher
western blot; rat	Liu X, Zhang J, Han W, Wang Y, Liu Y, Zhang Y, et al. Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats. Mol Med Rep. 2017;16:192-200 pubmed publisher
western blot; rat; 1:500; fig 5	Yu H, Shi L, Qi G, Zhao S, Gao Y, Li Y. Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Front Pharmacol. 2016;7:148 pubmed publisher
western blot; human	Zhang Y, Lin L, Jin Y, Lin Y, Cao Y, Zheng C. Overexpression of WNT5B promotes COLO 205 cell migration and invasion through the JNK signaling pathway. Oncol Rep. 2016;36:23-30 pubmed publisher
western blot; rat	Cong L, Chen W. Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats. Basic Clin Pharmacol Toxicol. 2016;119:193-201 pubmed publisher
flow cytometry; human	Iriyama N, Hatta Y, Takei M. Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes. Cancer Med. 2016;5:3223-3234 pubmed publisher
western blot; rat	Zhao H, Liu Z, Liu W, Han X, Zhao M. Betulin attenuates lung and liver injuries in sepsis. Int Immunopharmacol. 2016;30:50-6 pubmed publisher
western blot; dog	Król M, Mucha J, Majchrzak K, Homa A, Bulkowska M, Majewska A, et al. Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors. PLoS ONE. 2014;9:e83995 pubmed publisher
western blot; cow	Rosenzweig D, Ou S, Quinn T. P38 mitogen-activated protein kinase promotes dedifferentiation of primary articular chondrocytes in monolayer culture. J Cell Mol Med. 2013;17:508-17 pubmed publisher
western blot; cow	Rosenzweig D, Djap M, Ou S, Quinn T. Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis. Osteoarthritis Cartilage. 2012;20:1591-602 pubmed publisher

product information

sku :

bs-1640R

name :

JNK1+2+3 (T183+Y185) Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

JNK1+2+3 (THR183+TYR185)

modification :

Phosphorylation

modification site :

THR183+TYR185

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

170-210/427

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic phosphopeptide derived from human JNK1 around the phosphorylation site of Thr183/Tyr185

gene id link :

Entrez Gene: 5599

swiss prot :

P45983

swiss prot link :

Swiss Prot: P45983

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Bovine, Dog

size :

100 ul

price :

309.5 USD

background :

JNK1 isoforms display different binding patterns: beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; Stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK8

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage