product summary
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company name :
Bioss
product type :
antibody
product name :
CD146 Polyclonal Antibody
catalog :
bs-1618R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Bioss product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human
Zhan F, Liu X, Wang X. The Role of MicroRNA-143-5p in the Differentiation of Dental Pulp Stem Cells into Odontoblasts by Targeting Runx2 via the OPG/RANKL Signaling Pathway. J Cell Biochem. 2018;119:536-546 pubmed publisher
  • flow cytometry; rat
Zhang Y, Chen S, Liu B, Zhou H, Hu S, Zhou Y, et al. Exendin-4 promotes proliferation of adipose-derived stem cells through ERK and JNK signaling pathways. In Vitro Cell Dev Biol Anim. 2016;52:598-606 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
Hu J, Zeng B, Jiang X, Hu L, Meng Y, Zhu Y, et al. The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious. Int J Clin Exp Pathol. 2015;8:1525-34 pubmed
product information
sku :
bs-1618R
name :
CD146 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
CD146/MCAM
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
200-250/646
subcellular locations :
Extracellular
source :
KLH conjugated synthetic peptide derived from human CD146
gene id link :
Entrez Gene: 4162
swiss prot :
P43121
swiss prot link :
Swiss Prot: P43121
applications :
WB, FCM, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
CD146; MUC18; Cell surface glycoprotein MUC18; Cell surface glycoprotein P1H12; Melanoma cell adhesion molecule; Melanoma-associated antigen A32; Melanoma-associated antigen MUC18; S-endo 1 endothelial-associated antigen; MCAM
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.