FOX3/NeuN Polyclonal Antibody | Bioss bs-1613R product information

product summary

company name :

Bioss

product type :

antibody

product name :

FOX3/NeuN Polyclonal Antibody

catalog :

bs-1613R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse	Wang J, Tian W, Wang S, Wei W, Wu D, Wang H, et al. Anti-inflammatory and retinal protective effects of capsaicin on ischaemia-induced injuries through the release of endogenous somatostatin. Clin Exp Pharmacol Physiol. 2017;44:803-814 pubmed publisher
western blot; rat	Kopec A, Rivera P, Lacagnina M, Hanamsagar R, Bilbo S. Optimized solubilization of TRIzol-precipitated protein permits Western blotting analysis to maximize data available from brain tissue.. J Neurosci Methods. 2017;280:64-76 pubmed publisher
flow cytometry; rat	Song E, Gaudin A, King A, Seo Y, Suh H, Deng Y, et al. Surface chemistry governs cellular tropism of nanoparticles in the brain. Nat Commun. 2017;8:15322 pubmed publisher
immunohistochemistry - paraffin section; rat	Hu H, Lin R, Zhu X, Li Z, Chen L. Anti-inflammatory effects of Gualou Guizhi decoction in transient focal cerebral ischemic brains. [Corrected].. Mol Med Rep. 2015;12:3998 pubmed publisher
immunocytochemistry; human western blot; human; 1:100; fig 1	Fontes J, Ramsey J, Polk J, Koop A, Denisova J, Belousov A. Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin. PLoS ONE. 2015;10:e0125395 pubmed publisher
immunocytochemistry; mouse	Wei G, Chen Y, Chen D, Lai X, Liu D, Deng R, et al. β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 mice. J Alzheimers Dis. 2013;33:863-80 pubmed publisher
immunohistochemistry - paraffin section; mouse	Zhao W, Zhang J, Davis E, Rebeck G. Aging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector. Front Aging Neurosci. 2014;6:210 pubmed publisher
immunohistochemistry - paraffin section; rat	Jiang W, Tian J, Fu F, Zhu H, Hou J. Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury. Eur J Pharmacol. 2010;640:75-81 pubmed publisher
	Ridder K, Sevko A, Heide J, Dams M, Rupp A, Macas J, et al. Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment. Oncoimmunology. 2015;4:e1008371 pubmed
	Jiang W, Fu F, Tian J, Zhu H, Hou J. Curculigoside A attenuates experimental cerebral ischemia injury in vitro and vivo. Neuroscience. 2011;192:572-9 pubmed publisher
	Li H, Liang A, Guan F, Fan R, Chi L, Yang B. Regular treadmill running improves spatial learning and memory performance in young mice through increased hippocampal neurogenesis and decreased stress. Brain Res. 2013;1531:1-8 pubmed publisher
	Yu L, Chen C, Wang L, Kuang X, Liu K, Zhang H, et al. Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke. PLoS ONE. 2013;8:e55839 pubmed publisher
	Zhao W, Dumanis S, Tamboli I, Rodriguez G, Jo Ladu M, Moussa C, et al. Human APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer model. Hum Mol Genet. 2014;23:1365-75 pubmed publisher

product information

sku :

bs-1613R

name :

FOX3/NeuN Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

FOX3/NeuN

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

70-120/312

subcellular locations :

Cytoplasm, Nucleus

source :

KLH conjugated synthetic peptide derived from human NeuN

gene id link :

Entrez Gene: 146713

swiss prot :

A6NFN3

swiss prot link :

Swiss Prot: A6NFN3

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Vertebrate neuron-specific nuclear protein called NeuN (Neuronal Nuclei) is an excellent marker for neurons in primary cultures and in retinoic acid-stimulated P19 cells. It is also useful for identifying neurons in transplants. NeuN is a neuron-specific, DNA-binding nuclear protein in vertebrates. In mice, NeuN is observed in most neuronal cell types throughout the nervous system, including cerebellum, cerebral cortex, hippocampus, thalamus and spinal cord, as well as the dorsal root ganglia, sympathetic chain ganglia and enteric ganglia of the peripheral nervous system. NeuN immunoreactivity is first observed in neurons when they become post-mitotic and are initiating cellular and morphological differentiation. No staining is observed in proliferative zones. NeuN has been used as an immunohistochemical marker for excitotoxic lesions of the brain as well as in the diagnosis of a wide range of human tissue specimens from the central and peripheral nervous systems.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

FOX3; NEUN; FOX-3; HRNBP3; RNA binding protein fox-1 homolog 3; Fox-1 homolog C; RBFOX3

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage