ERK1 (T203/Y205) + ERK2 (T183/Y185) Polyclonal Antibody | Bioss bs-1522R product information

product summary

company name :

Bioss

product type :

antibody

product name :

ERK1 (T203/Y205) + ERK2 (T183/Y185) Polyclonal Antibody

catalog :

bs-1522R

quantity :

100 ul

price :

309.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, cow

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Liu X, Zhang J, Han W, Wang Y, Liu Y, Zhang Y, et al. Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats. Mol Med Rep. 2017;16:192-200 pubmed publisher
western blot; rat	Zhao H, Xue Y, Guo Y, Sun Y, Liu D, Wang X. Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension. Int Immunopharmacol. 2017;42:115-121 pubmed publisher
western blot; rat; 1:500; fig 5	Yu H, Shi L, Qi G, Zhao S, Gao Y, Li Y. Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Front Pharmacol. 2016;7:148 pubmed publisher
western blot; rat	Cong L, Chen W. Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats. Basic Clin Pharmacol Toxicol. 2016;119:193-201 pubmed publisher
western blot; rat	Zhao H, Liu Z, Liu W, Han X, Zhao M. Betulin attenuates lung and liver injuries in sepsis. Int Immunopharmacol. 2016;30:50-6 pubmed publisher
western blot; cow	Rosenzweig D, Djap M, Ou S, Quinn T. Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis. Osteoarthritis Cartilage. 2012;20:1591-602 pubmed publisher

product information

sku :

bs-1522R

name :

ERK1 (T203/Y205) + ERK2 (T183/Y185) Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

ERK1 (Thr203/Tyr205) + ERK2 (Thr183/Tyr185)

modification :

Phosphorylation

modification site :

Thr183/Tyr 185

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

160-200/358

subcellular locations :

Cytoplasm

source :

KLH conjugated synthetic phosphopeptide derived from mouse ERK2 around the phosphorylation site of Thr183 and Tyr 185

gene id link :

Entrez Gene: 26413

swiss prot :

P63085

swiss prot link :

Swiss Prot: P63085

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Bovine

size :

100 ul

price :

309.5 USD

background :

Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity (By similarity).

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

ERK; Erk2; MAPK2; PRKM2; Prkm1; C78273; p41mapk; p42mapk; AA47128; AU18647; 93612K14Rik; Mitogen-activated protein kinase 1; MAP kinase 1; MAPK 1; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2; Mapk1; Mapk

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage