BCL2L1 Polyclonal Antibody | Bioss bs-1336R product information

product summary

company name :

Bioss

product type :

antibody

product name :

BCL2L1 Polyclonal Antibody

catalog :

bs-1336R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, cow, pig, sheep

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rat	Abdel-Hamid N, El-Azab M, Moustafa Y. Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model. Naunyn Schmiedebergs Arch Pharmacol. 2017;: pubmed publisher
western blot; cow; loading ...; fig 1c western blot; pig	Zhao Y, Zhang W, Liu X, Zhang P, Hao Y, Li L, et al. Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways. Sci Rep. 2016;6:37884 pubmed publisher
immunohistochemistry - paraffin section; sheep western blot; sheep; loading ...; fig 6e	Wang Y, Zhao Y, Yu S, Feng Y, Zhang H, Kou X, et al. Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis. Toxicol Appl Pharmacol. 2016;313:149-158 pubmed publisher
ELISA; mouse	Zhu Z, Wang Y, Liang Z, Wang W, Zhang H, Li B, et al. Regulation of cell transformation by Rb-controlled redox homeostasis. PLoS ONE. 2014;9:e102582 pubmed publisher

product information

sku :

bs-1336R

name :

BCL2L1 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

BCL2L1

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

70-120/233

subcellular locations :

Helical

source :

KLH conjugated synthetic peptide derived from human BCL2L1

gene id link :

Entrez Gene: 598

swiss prot :

Q07817

swiss prot link :

Swiss Prot: Q07817

applications :

WB, ELISA, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), ELISA(1:500-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F() activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. Isoform Bcl-X(S) promotes apoptosis.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

BCLX; BCL2L; BCLXL; BCLXS; Bcl-X; bcl-xL; bcl-xS; PPP1R52; BCL-XL/S; Bcl-2-like protein 1; Bcl2-L-1; Apoptosis regulator Bcl-X; BCL2L1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage