product summary
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company name :
Bioss
product type :
antibody
product name :
NFKBIA/IKB alpha Polyclonal Antibody
catalog :
bs-1287R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; rat
Sun G, Yang W, Zhang Y, Zhao M. Esculentoside A ameliorates cecal ligation and puncture-induced acute kidney injury in rats. Exp Anim. 2017;66:303-312 pubmed publisher
  • western blot; rat
Liu X, Zhang J, Han W, Wang Y, Liu Y, Zhang Y, et al. Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats. Mol Med Rep. 2017;16:192-200 pubmed publisher
  • western blot; rat; 1:500; fig 4
Han J, Xie Y, Sui F, Liu C, Du X, Liu C, et al. Zisheng Shenqi decoction ameliorates monosodium urate crystal-induced gouty arthritis in rats through anti-inflammatory and anti-oxidative effects. Mol Med Rep. 2016;14:2589-97 pubmed publisher
  • western blot; mouse
Gao W, Guo Y, Wang C, Lin Y, Yu L, Sheng T, et al. Indirubin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice through the inhibition of inflammation and the induction of Foxp3-expressing regulatory T cells. Acta Histochem. 2016;118:606-614 pubmed publisher
  • western blot; rat; 1:500; fig 5
Yu H, Shi L, Qi G, Zhao S, Gao Y, Li Y. Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo. Front Pharmacol. 2016;7:148 pubmed publisher
  • western blot; rat
Li Y, Zhang Q, Qi D, Zhang L, Yi L, Li Q, et al. Valproate ameliorates nitroglycerin-induced migraine in trigeminal nucleus caudalis in rats through inhibition of NF-?B. J Headache Pain. 2016;17:49 pubmed publisher
  • western blot; rat
Zhao H, Zheng Q, Hu X, Shen H, Li F. Betulin attenuates kidney injury in septic rats through inhibiting TLR4/NF-κB signaling pathway. Life Sci. 2016;144:185-93 pubmed publisher
  • western blot; rat
Zhao H, Liu Z, Liu W, Han X, Zhao M. Betulin attenuates lung and liver injuries in sepsis. Int Immunopharmacol. 2016;30:50-56 pubmed publisher
  • western blot; rat
Yan X, Wu L, Li B, Meng X, Dai H, Zheng Y, et al. Cyanidin-3-O-glucoside Induces Apoptosis and Inhibits Migration of Tumor Necrosis Factor-α-Treated Rat Aortic Smooth Muscle Cells. Cardiovasc Toxicol. 2016;16:251-9 pubmed publisher
  • western blot; mouse
Ma J, Liu R, Wang X, Liu Q, Chen Y, Valle R, et al. Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals. ACS Nano. 2015;9:10498-515 pubmed publisher
  • western blot; mouse
Yan X, Wu L, Li B, Meng X, Dai H, Zheng Y, et al. Cyanidin-3-O-glucoside attenuates acute lung injury in sepsis rats. J Surg Res. 2015;199:592-600 pubmed publisher
  • western blot; rat
Yang J, Wang H, Zhang Y, Yang Y, Lu M, Zhang J, et al. Astragaloside IV attenuates inflammatory cytokines by inhibiting TLR4/NF-?B signaling pathway in isoproterenol-induced myocardial hypertrophy. J Ethnopharmacol. 2013;150:1062-70 pubmed
  • western blot; rat
Jiang W, Tian J, Fu F, Zhu H, Hou J. Neuroprotective efficacy and therapeutic window of Forsythoside B: in a rat model of cerebral ischemia and reperfusion injury. Eur J Pharmacol. 2010;640:75-81 pubmed publisher
product information
sku :
bs-1287R
name :
NFKBIA/IKB alpha Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
NFKBIA/IKB alpha
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
5-34/314
subcellular locations :
Cytoplasm, Nucleus
source :
KLH conjugated synthetic peptide derived from mouse IKB alpha
gene id link :
Entrez Gene: 18035
swiss prot :
Q9Z1E3
swiss prot link :
Swiss Prot: Q9Z1E3
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
Nfkbi; AI46215; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Nfkbia; Ikba
lead time :
3 to 5 business days.
more info or order :
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.