product summary
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company name :
Bioss
product type :
antibody
product name :
Stella/DPPA3 Polyclonal Antibody
catalog :
bs-12280R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, pig
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Bioss product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; pig
Wasielak M, Wiesak T, Bogacka I, Jalali B, Bogacki M. Zygote arrest 1, nucleoplasmin 2, and developmentally associated protein 3 mRNA profiles throughout porcine embryo development in vitro. Theriogenology. 2016;86:2254-2262 pubmed publisher
product information
sku :
bs-12280R
name :
Stella/DPPA3 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Stella/DPPA3
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
100-150/159
subcellular locations :
Cytoplasm, Nucleus
source :
KLH conjugated synthetic peptide derived from human Stella/DPPA3
gene id link :
Entrez Gene: 359787
swiss prot :
Q6W0C5
swiss prot link :
Swiss Prot: Q6W0C5
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human
size :
100 ul
price :
289.5 USD
background :
Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at 'Lys-9' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis (By similarity).
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
STELLA; Developmental pluripotency-associated protein 3; Stella-related protein; DPPA3; STELLAR
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.