product summary
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company name :
Bioss
product type :
antibody
product name :
Frizzled 9/CD349 Polyclonal Antibody
catalog :
bs-11842R
quantity :
100 ul
price :
279 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 1
| Published Application/Species/Sample/Dilution | Reference |
|---|---|
| Vasyliev R, Rodnichenko A, Gubar O, Zlatska A, Gordiienko I, Novikova S, et al. Large-scale expansion and characterization of human adult neural crest-derived multipotent stem cells from hair follicle for regenerative medicine applications. Exp Oncol. 2017;39:171-180 pubmed
|
product information
sku :
bs-11842R
name :
Frizzled 9/CD349 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Frizzled 9/CD349
specificity :
This antibody may have slight cross reactivity with Frizzled 10.
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
180-229/591
subcellular locations :
Extracellular
source :
KLH conjugated synthetic peptide derived from human Frizzled 9/CD349
gene id link :
Entrez Gene: 8326
swiss prot :
O00144
swiss prot link :
Swiss Prot: O00144
applications :
IHC-P, IF(IHC-P)
applications with dilutions :
IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
279 USD
background :
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
FZD3; CD349; Frizzled-9; Fz-9; hFz9; FzE6; FZD9
lead time :
3 to 5 business days.
more info or order :
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.