Caspase 12 Polyclonal Antibody | Bioss bs-1105R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Caspase 12 Polyclonal Antibody

catalog :

bs-1105R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
western blot; rat	Wang Y, Xuan L, Cui X, Wang Y, Chen S, Wei C, et al. Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes.. PLoS ONE. 2017;12:e0173469 pubmed publisher
western blot; rat	Wang Y, Wang Y, Huang X, Yang Y, Zhao Y, Wei C, et al. Ibutilide protects against cardiomyocytes injury via inhibiting endoplasmic reticulum and mitochondrial stress pathways. Heart Vessels. 2017;32:208-215 pubmed publisher
western blot; rat	Yu H, Zhang H, Zhao W, Guo L, Li X, Li Y, et al. Gypenoside Protects against Myocardial Ischemia-Reperfusion Injury by Inhibiting Cardiomyocytes Apoptosis via Inhibition of CHOP Pathway and Activation of PI3K/Akt Pathway In Vivo and In Vitro. Cell Physiol Biochem. 2016;39:123-36 pubmed publisher
immunohistochemistry - paraffin section; rat	Zhang L, Zhang H, Lv M, Jia J, Fan Y, Tian X, et al. Increased expression of 78 kD glucose-regulated protein promotes cardiomyocyte apoptosis in a rat model of liver cirrhosis. Int J Clin Exp Pathol. 2015;8:9256-63 pubmed
western blot; rat	Zhou Y, Zhou Y, Yu S, Wu J, Chen Y, Zhao Y. Sulfiredoxin-1 exerts anti-apoptotic and neuroprotective effects against oxidative stress-induced injury in rat cortical astrocytes following exposure to oxygen-glucose deprivation and hydrogen peroxide. Int J Mol Med. 2015;36:43-52 pubmed publisher
immunohistochemistry - paraffin section; rat	Zhang H, Lv M, Zhao Z, Jia J, Zhang L, Xiao P, et al. Glucose-regulated protein 78 may play a crucial role in promoting the pulmonary microvascular remodeling in a rat model of hepatopulmonary syndrome. Gene. 2014;545:156-62 pubmed publisher

product information

sku :

bs-1105R

name :

Caspase 12 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Caspase 12

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

240-290/419

subcellular locations :

Cytoplasm

source :

KLH conjugated synthetic peptide derived from mouse Caspase 12

gene id link :

Entrez Gene: 12364

swiss prot :

O08736

swiss prot link :

Swiss Prot: O08736

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

Caspase-12; CASP-12; Casp12

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage