MCP1 Polyclonal Antibody | Bioss bs-1101R product information

product summary

company name :

Bioss

product type :

antibody

product name :

MCP1 Polyclonal Antibody

catalog :

bs-1101R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Bioss product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:1500; loading ...; fig 3a	Yagura K, Ohtaki H, Tsumuraya T, Sato A, Miyamoto K, Kawada N, et al. The enhancement of CCL2 and CCL5 by human bone marrow-derived mesenchymal stem/stromal cells might contribute to inflammatory suppression and axonal extension after spinal cord injury. PLoS ONE. 2020;15:e0230080 pubmed publisher
immunohistochemistry - frozen section; mouse	Kugo H, Zaima N, Onozato M, Miyamoto C, Hashimoto K, Yanagimoto K, et al. Suppressive effects of dietary EPA-rich fish oil on the degradation of elastin fibers in the aortic wall in nicotine-administered mice. Food Funct. 2017;8:2829-2835 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100; tbl 3 immunohistochemistry - paraffin section; mouse	Kuracha M, Thomas P, Loggie B, Govindarajan V. Patient-derived xenograft mouse models of pseudomyxoma peritonei recapitulate the human inflammatory tumor microenvironment. Cancer Med. 2016;5:711-9 pubmed publisher

product information

sku :

bs-1101R

name :

MCP1 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

MCP1

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

95-145/148

subcellular locations :

Secreted

source :

KLH conjugated synthetic peptide derived from rat MCP-1

gene id link :

Entrez Gene: 24770

swiss prot :

P14844

swiss prot link :

Swiss Prot: P14844

applications :

IHC-P, IF(IHC-P)

applications with dilutions :

IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Monomer or homodimer; in equilibrium. Binds to CCR2 and CCR4. Is tethered on endothelial cells by glycosaminoglycan (GAG) side chains of proteoglycans. Processing at the N-terminus can regulate receptor and targetcell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. Genetic variations in CCL2 determine Mycobacterium tuberculosis susceptibility Belongs to the intercrine beta (chemokine CC) family. The MCP-1( the monocyte chemotactic protein1) has many pits that regulates the function toward sex to turn to record the factor, it can induce to have relation with inflammation with the immunity various genes turn to record.The immunity MCP-1 set turns the male signal to mainly locate the afterbirth syrup inside.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

MCP-1; Scya2; Sigje; C-C motif chemokine 2; Immediate-early serum-responsive protein JE; Monocyte chemoattractant protein 1; Monocyte chemotactic protein 1; Small-inducible cytokine A2; Ccl2; Je; Mcp1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage