Nrf2 Polyclonal Antibody | Bioss bs-1074R product information

product summary

company name :

Bioss

product type :

antibody

product name :

Nrf2 Polyclonal Antibody

catalog :

bs-1074R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
western blot; human	Zhang J, Wang X, Hao L, Wang H, Zhang X, Muhammad I, et al. Nrf2 is crucial for the down-regulation of Cyp7a1 induced by arachidonic acid in Hepg2 cells.. Environ Toxicol Pharmacol. 2017;52:21-26 pubmed publisher
western blot; mouse	Cao Z, Huang S, Dou C, Xiang Q, Dong S. Cyanidin suppresses autophagic activity regulating chondrocyte hypertrophic differentiation. J Cell Physiol. 2017;: pubmed publisher
western blot; mouse	Shen H, Wu N, Wang Y, Zhao H, Zhang L, Li T, et al. Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis.. Int Immunopharmacol. 2017;46:16-22 pubmed publisher
western blot; human	Zhang B, Dong J, Chen Y, Liu Y, Huang S, Zhong X, et al. Nrf2 mediates the protective effects of homocysteine by increasing the levels of GSH content in HepG2 cells. Mol Med Rep. 2017;16:597-602 pubmed publisher
immunohistochemistry - paraffin section; rat	Yu D, Bei Y, Li Y, Han W, Zhong Y, Liu F, et al. In vitro the differences of inflammatory and oxidative reactions due to sulfur mustard induced acute pulmonary injury underlying intraperitoneal injection and intratracheal instillation in rats.. Int Immunopharmacol. 2017;47:78-87 pubmed publisher
western blot; rat	Zeng X, Li X, Zhang Q, Liu Q, Li L, Xiong Y, et al. Tert-Butylhydroquinone Protects Liver Against Ischemia/Reperfusion Injury in Rats Through Nrf2-Activating Anti-Oxidative Activity.. Transplant Proc. 2017;49:366-372 pubmed publisher
western blot; rat	Jiang W, Li M, He F, Yao W, Bian Z, Wang X, et al. Protective Effects of Asiatic Acid Against Spinal Cord Injury-Induced Acute Lung Injury in Rats. Inflammation. 2016;39:1853-1861 pubmed
western blot; rat	Yu H, Shi L, Zhao S, Sun Y, Gao Y, Sun Y, et al. Triptolide Attenuates Myocardial Ischemia/Reperfusion Injuries in Rats by Inducing the Activation of Nrf2/HO-1 Defense Pathway. Cardiovasc Toxicol. 2016;16:325-35 pubmed publisher
western blot; human	Wang P, Peng X, Wei Z, Wei F, Wang W, Ma W, et al. Geraniin exerts cytoprotective effect against cellular oxidative stress by upregulation of Nrf2-mediated antioxidant enzyme expression via PI3K/AKT and ERK1/2 pathway. Biochim Biophys Acta. 2015;1850:1751-61 pubmed publisher
western blot; rat	Lv R, Mao N, Wu J, Lu C, Ding M, Gu X, et al. Neuroprotective effect of allicin in a rat model of acute spinal cord injury. Life Sci. 2015;143:114-23 pubmed publisher
western blot; rat	Hsu W, Lee B, Li C, Hsu Y, Pan T. Monascin and AITC attenuate methylglyoxal-induced PPARγ phosphorylation and degradation through inhibition of the oxidative stress/PKC pathway depending on Nrf2 activation. J Agric Food Chem. 2013;61:5996-6006 pubmed publisher
western blot; human	Lee B, Hsu W, Hsu Y, Pan T. Dimerumic acid attenuates receptor for advanced glycation endproducts signal to inhibit inflammation and diabetes mediated by Nrf2 activation and promotes methylglyoxal metabolism into d-lactic acid. Free Radic Biol Med. 2013;60:7-16 pubmed publisher
western blot; mouse	Lee B, Lee C, Cheng Y, Chang W, Hsu W, Wu S. Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia. Food Chem Toxicol. 2013;62:492-8 pubmed publisher
western blot; rat	Lee B, Hsu W, Chang Y, Kuo H, Hsu Y, Pan T. Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. Free Radic Biol Med. 2012;53:2008-16 pubmed publisher
western blot; mouse	Lee B, Hsu W, Hsu Y, Pan T. Suppression of dimerumic acid on hepatic fibrosis caused from carboxymethyl-lysine (CML) by attenuating oxidative stress depends on Nrf2 activation in hepatic stellate cells (HSCs). Food Chem Toxicol. 2013;62:413-9 pubmed publisher
immunohistochemistry - paraffin section; rat	Wang Y, Fang J, Huang S, Chen L, Fan G, Wang C. The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats. Environ Toxicol Pharmacol. 2013;35:109-16 pubmed publisher
	Lee B, Hsu W, Huang T, Chang Y, Hsu Y, Pan T. Effects of monascin on anti-inflammation mediated by Nrf2 activation in advanced glycation end product-treated THP-1 monocytes and methylglyoxal-treated wistar rats. J Agric Food Chem. 2013;61:1288-98 pubmed publisher
	Lee C, Lee B, Wu S. Actinidia callosa peel (kiwi fruit) ethanol extracts protected neural cells apoptosis induced by methylglyoxal through Nrf2 activation. Pharm Biol. 2014;52:628-36 pubmed publisher

product information

sku :

bs-1074R

name :

Nrf2 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

Nrf2

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

430-480/605

source :

KLH conjugated synthetic peptide derived from human Nrf2

gene id link :

Entrez Gene: 4780

swiss prot :

Q16236

swiss prot link :

Swiss Prot: Q16236

applications :

WB, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2; NFE2L2

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage