product summary
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company name :
Bioss
product type :
antibody
product name :
Cyclooxygenase 2 Polyclonal Antibody
catalog :
bs-10411R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; rat
Zheng J, Liu Z, Li W, Tang J, Zhang D, Tang X. Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats. J Neurosurg. 2016;:1-9 pubmed
Niu X, Wang Y, Li W, Mu Q, Li H, Yao H, et al. Protective effects of Isofraxidin against lipopolysaccharide-induced acute lung injury in mice. Int Immunopharmacol. 2015;24:432-9 pubmed publisher
product information
sku :
bs-10411R
name :
Cyclooxygenase 2 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
Cyclooxygenase 2
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
320-365/604
subcellular locations :
Intracellular
source :
KLH conjugated synthetic peptide derived from human Cyclooxygenase 2
gene id link :
Entrez Gene: 5743
swiss prot :
P35354
swiss prot link :
Swiss Prot: P35354
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS; Prostaglandin G/H synthase 2; Cyclooxygenase-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; Prostaglandin-endoperoxide synthase 2; PTGS2
lead time :
3 to 5 business days.
more info or order :
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.