TLR2 Polyclonal Antibody | Bioss bs-1019R product information

product summary

company name :

Bioss

product type :

antibody

product name :

TLR2 Polyclonal Antibody

catalog :

bs-1019R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, cow

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other

more info or order :

Bioss product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; rat	Hardigan T, Abdul Y, Ergul A. Linagliptin reduces effects of ET-1 and TLR2-mediated cerebrovascular hyperreactivity in diabetes. Life Sci. 2016;159:90-96 pubmed publisher
other; rat	Mannic T, Satta N, Pagano S, Python M, Virzi J, Montecucco F, et al. CD14 as a Mediator of the Mineralocorticoid Receptor-Dependent Anti-apolipoprotein A-1 IgG Chronotropic Effect on Cardiomyocytes. Endocrinology. 2015;156:4707-19 pubmed publisher
western blot; cow	Tan Y, Tseng P, Wang D, Zhang H, Hunter K, Hertzberg J, et al. Stiffening-induced high pulsatility flow activates endothelial inflammation via a TLR2/NF-?B pathway. PLoS ONE. 2014;9:e102195 pubmed publisher
other; rat	Chen X, Yu G, Fan S, Bian M, Ma H, Lu J, et al. Sargassum fusiforme polysaccharide activates nuclear factor kappa-B (NF-?B) and induces cytokine production via Toll-like receptors. Carbohydr Polym. 2014;105:113-20 pubmed publisher
	Barreiros D, Pucinelli C, Oliveira K, Paula Silva F, Nelson Filho P, Silva L, et al. Immunohistochemical and mRNA expression of RANK, RANKL, OPG, TLR2 and MyD88 during apical periodontitis progression in mice. J Appl Oral Sci. 2018;26:e20170512 pubmed publisher
	Zhu Y, Wang C, Song G, Zang S, Liu Y, Li L. Toll-like receptor-2 and -4 are associated with hyperlipidemia. Mol Med Rep. 2015;12:8241-6 pubmed publisher
	Takanashi N, Tomosada Y, Villena J, Murata K, Takahashi T, Chiba E, et al. Advanced application of bovine intestinal epithelial cell line for evaluating regulatory effect of lactobacilli against heat-killed enterotoxigenic Escherichia coli-mediated inflammation. BMC Microbiol. 2013;13:54 pubmed publisher
	Tomofuji T, Ekuni D, Azuma T, Irie K, Endo Y, Kasuyama K, et al. Involvement of toll-like receptor 2 and 4 in association between dyslipidemia and osteoclast differentiation in apolipoprotein E deficient rat periodontium. Lipids Health Dis. 2013;12:1 pubmed publisher
	Tang L, Zhou X, Wang Q, Zhang L, Wang Y, Li X, et al. Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts. Arch Oral Biol. 2011;56:1064-72 pubmed publisher

product information

sku :

bs-1019R

name :

TLR2 Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

TLR2

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

730-780/784

subcellular locations :

Cytoplasm

source :

KLH conjugated synthetic peptide derived from human TLR2

gene id link :

Entrez Gene: 7097

swiss prot :

O60603

swiss prot link :

Swiss Prot: O60603

applications :

WB, FCM, IHC-P, IF(IHC-P)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

cross reactive species :

Human, Mouse, Rat, Bovine

size :

100 ul

price :

289.5 USD

background :

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR6.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

TIL4; CD282; Toll-like receptor 2; Toll/interleukin-1 receptor-like protein 4; TLR2

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage