E cadherin Polyclonal Antibody | Bioss bs-10009R product information

product summary

company name :

Bioss

product type :

antibody

product name :

E cadherin Polyclonal Antibody

catalog :

bs-10009R

quantity :

100 ul

price :

289.5 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Bioss product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human	Yun Y, Gao R, Yue H, Guo L, Li G, Sang N. Sulfate Aerosols Promote Lung Cancer Metastasis by Epigenetically Regulating the Epithelial-to-Mesenchymal Transition (EMT). Environ Sci Technol. 2017;51:11401-11411 pubmed publisher
immunohistochemistry - paraffin section; mouse western blot; mouse	Borin T, Shankar A, Angara K, Rashid M, Jain M, Iskander A, et al. HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model. PLoS ONE. 2017;12:e0178830 pubmed publisher
western blot; human	Wang J, Nikhil K, Viccaro K, Chang L, White J, Shah K. Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer. BMC Biol. 2017;15:10 pubmed publisher
western blot; rat	Chen C, Cheng C, Chen Y, Sue Y, Liu C, Cheng T, et al. MicroRNA-328 inhibits renal tubular cell epithelial-to-mesenchymal transition by targeting the CD44 in pressure-induced renal fibrosis. PLoS ONE. 2014;9:e99802 pubmed publisher
	Wang J, Nikhil K, Viccaro K, Chang L, Jacobsen M, Sandusky G, et al. The Aurora-A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma. J Cell Sci. 2017;130:1078-1093 pubmed publisher
	Jayachandran M, Lugo G, Heiling H, Miller V, Rule A, Lieske J. Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. Biol Sex Differ. 2015;6:2 pubmed publisher
	Neelam S, Brooks M, Cammarata P. Lenticular cytoprotection, part 2: link between glycogen synthase kinase-3Î², epithelial to mesenchymal transition, and mitochondrial depolarization. Mol Vis. 2014;20:1758-75 pubmed

product information

sku :

bs-10009R

name :

E cadherin Polyclonal Antibody

category :

Primary Antibody

conjugation :

Unconjugated

host :

Rabbit

target protein :

E cadherin

modification :

Unmodified

clonality :

Polyclonal

isotype :

IgG

concentration :

1ug/ul

public immunogen range :

410-460/882

subcellular locations :

Extracellular

source :

KLH conjugated synthetic peptide derived from human E-cadherin

gene id link :

Entrez Gene: 999

swiss prot :

P12830

swiss prot link :

Swiss Prot: P12830

applications :

WB, FCM, IHC-P, IF(IHC-P), IF(ICC)

applications with dilutions :

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

cross reactive species :

Human, Mouse, Rat

size :

100 ul

price :

289.5 USD

background :

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.

purification :

Purified by Protein A.

storage :

Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.

synonyms :

UVO; CDHE; ECAD; LCAM; Arc-1; CD324; Cadherin-1; CAM 12/8; Epithelial cadherin; E-cadherin; Uvomorulin; CDH1

lead time :

3 to 5 business days.

more info or order :

Bioss product webpage