product summary
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company name :
Bioss
product type :
antibody
product name :
PDX1 Polyclonal Antibody
catalog :
bs-0923R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
goat, human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Bioss product webpage
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; goat
  • immunocytochemistry; goat
Zheng L, Zhai Y, Li N, Ma F, Zhu H, Du X, et al. The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation. Sci Rep. 2016;6:37414 pubmed publisher
  • western blot; mouse
Jian R, Mao L, Xu Y, Li X, Wang F, Luo X, et al. Generation of insulin-producing cells from C3H10T1/2 mesenchymal progenitor cells. Gene. 2015;562:107-16 pubmed publisher
Wang H, Ren Y, Hu X, Ma M, Wang X, Liang H, et al. Effect of Wnt Signaling on the Differentiation of Islet β-Cells from Adipose-Derived Stem Cells.. Biomed Res Int. 2017;2017:2501578 pubmed publisher
Hefei W, Yu R, Haiqing W, Xiao W, Jingyuan W, Dongjun L. Morphological characteristics and identification of islet-like cells derived from rat adipose-derived stem cells cocultured with pancreas adult stem cells. Cell Biol Int. 2015;39:253-63 pubmed publisher
product information
sku :
bs-0923R
name :
PDX1 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
PDX1
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
190-222/284
subcellular locations :
Cytoplasm, Nucleus
source :
KLH conjugated synthetic peptide derived from mouse PDX1
gene id link :
Entrez Gene: 18609
swiss prot :
P52946
swiss prot link :
Swiss Prot: P52946
applications :
WB, IHC-P, IF(ICC)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(ICC)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
289.5 USD
background :
Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
Ipf1; IDX-1; IPF-1; Mody4; STF-1; pdx-1; Pancreas/duodenum homeobox protein 1; Insulin promoter factor 1; Islet/duodenum homeobox 1; Somatostatin-transactivating factor 1; Pdx1
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.