product summary
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company name :
Bioss
product type :
antibody
product name :
MCKD2 Polyclonal Antibody
catalog :
bs-0916R
quantity :
100 ul
price :
279 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Bioss product webpage
citations: 1
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Cho W, Song J, Oh S, Kim M, Ko Y, Lee H, et al. Fate of Neutrophils during the Recovery Phase of Ischemia/Reperfusion Induced Acute Kidney Injury. J Korean Med Sci. 2017;32:1616-1625 pubmed publisher
product information
sku :
bs-0916R
name :
MCKD2 Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
MCKD2/UMOD
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
120-170/642
subcellular locations :
Secreted, Cell membrane
source :
KLH conjugated synthetic peptide derived from mouse MCKD2
gene id link :
Entrez Gene: 22242
swiss prot :
Q91X17
swiss prot link :
Swiss Prot: Q91X17
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Rat
size :
100 ul
price :
279 USD
background :
Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelial (By similarity). Uromodulin, secreted form: Secreted into urine after proteolytically cleaveage. Into the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
THP; Urehd1; urehr4; Uromodulin; Tamm-Horsfall urinary glycoprotein; Umod
lead time :
3 to 5 business days.
more info or order :
Bioss product webpage
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.