product summary
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company name :
Bioss
product type :
antibody
product name :
LDL receptor Polyclonal Antibody
catalog :
bs-0705R
quantity :
100 ul
price :
289.5 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; human
Kou S, Han B, Wang Y, Huang T, He K, Han Y, et al. Synergetic cholesterol-lowering effects of main alkaloids from Rhizoma Coptidis in HepG2 cells and hypercholesterolemia hamsters. Life Sci. 2016;151:50-60 pubmed publisher
  • immunohistochemistry - paraffin section; rat
Jia L, Song N, Yang G, Ma Y, Li X, Lu R, et al. Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. Mol Med Rep. 2016;13:4627-35 pubmed publisher
Wu H, He K, Wang Y, Xue D, Ning N, Zou Z, et al. The antihypercholesterolemic effect of jatrorrhizine isolated from Rhizoma Coptidis. Phytomedicine. 2014;21:1373-81 pubmed publisher
product information
sku :
bs-0705R
name :
LDL receptor Polyclonal Antibody
category :
Primary Antibody
conjugation :
Unconjugated
host :
Rabbit
target protein :
LDL receptor
modification :
Unmodified
clonality :
Polyclonal
isotype :
IgG
concentration :
1ug/ul
public immunogen range :
811-850/860
subcellular locations :
Cytoplasm
source :
KLH conjugated synthetic peptide derived from human LDL-R
gene id link :
Entrez Gene: 3949
swiss prot :
P01130
swiss prot link :
Swiss Prot: P01130
applications :
WB, IHC-P, IF(IHC-P)
applications with dilutions :
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
cross reactive species :
Human, Mouse, Other Species
cross reactive species details :
Hamster
size :
100 ul
price :
289.5 USD
background :
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
purification :
Purified by Protein A.
storage :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
synonyms :
FH; FHC; LDLCQ2; Low-density lipoprotein receptor; LDL receptor; LDLR
lead time :
3 to 5 business days.
more info or order :
company information
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
800-501-7654
headquarters: USA
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.